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    F39B2.3 Enoyl reductase (ER) domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173346, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F39B2.3
    Official Full Name
    Enoyl reductase (ER) domain-containing protein
    Primary source
    WormBase:WBGene00009554
    Locus tag
    CELE_F39B2.3
    See related
    AllianceGenome:WB:WBGene00009554
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable NADPH binding activity; NADPH:quinone reductase activity; and mRNA 3'-UTR binding activity. Predicted to be active in cytosol. Orthologous to human CRYZ (crystallin zeta). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F39B2.3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (14788125..14789517, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene SH2 domain-containing protein Neighboring gene Mediator of RNA polymerase II transcription subunit 23 Neighboring gene Ubiquitin-conjugating enzyme E2 Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables NADPH binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables NADPH:quinone reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Enoyl reductase (ER) domain-containing protein
    NP_493577.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14788125..14789517 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061176.5 → NP_493577.1  Enoyl reductase (ER) domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493577.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45496
      Conserved Domains (1) summary
      cd08253
      Location:10 → 326
      zeta_crystallin; Zeta-crystallin with NADP-dependent quinone reductase activity (QOR)
    Nucleotide Protein
    Heading Accession and Version

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