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    cyp-29A3 Cytochrome P450 [ Caenorhabditis elegans ]

    Gene ID: 189649, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cyp-29A3
    Official Full Name
    Cytochrome P450
    Primary source
    WormBase:WBGene00021412
    Locus tag
    CELE_Y38C9B.1
    See related
    AllianceGenome:WB:WBGene00021412
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Orthologous to human CYP4V2 (cytochrome P450 family 4 subfamily V member 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cyp-29A3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (59239..63633)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene LITAF domain-containing protein Neighboring gene Serpentine Receptor, class T Neighboring gene Uncharacterized protein Neighboring gene FH2 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of CYP eicosanoids in the regulation of pharyngeal pumping and food uptake in Caenorhabditis elegans. Zhou Y, et al. J Lipid Res, 2015 Nov. PMID 26399467, Free PMC Article
    2. N6-adenosine methylation of ribosomal RNA affects lipid oxidation and stress resistance. Liberman N, et al. Sci Adv, 2020 Apr. PMID 32494643, Free PMC Article
    3. Cytochrome P450-dependent metabolism of eicosapentaenoic acid in the nematode Caenorhabditis elegans. Kulas J, et al. Arch Biochem Biophys, 2008 Apr 1. PMID 18282462
    4. Eicosapentaenoic acid influences the pathogenesis of Candida albicans in Caenorhabditis elegans via inhibition of hyphal formation and stimulation of the host immune response. Mokoena NZ, et al. Med Microbiol Immunol, 2023 Oct. PMID 37672050, Free PMC Article
    5. Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin. Karengera A, et al. Ecotoxicol Environ Saf, 2022 Mar 15. PMID 35219257

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cytochrome P450
    NP_503130.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      59239..63633
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070729.7 → NP_503130.2  Cytochrome P450 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503130.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N525
      Conserved Domains (1) summary
      pfam00067
      Location:37 → 477
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version

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