C08B6.8 Exonuclease domain-containing protein;putative oligoribonuclease [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C08B6.8
Official Full Name: Exonuclease domain-containing protein;putative oligoribonuclease
Primary source: WormBase:WBGene00007429
Locus tag: CELE_C08B6.8
See related: AllianceGenome:WB:WBGene00007429
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to be active in mitochondrion. Is expressed in several structures, including anal depressor muscle; egg-laying apparatus; excretory cell; intestine; and nervous system. Orthologous to human REXO2 (RNA exonuclease 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C08B6.8 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 3

Sequence:: Chromosome: V; NC_003283.11 (10134643..10143014)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

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Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C08B6.8 (e-PCR)
- UniSTS:321918

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables 3'-5'-RNA exonuclease activity	IEA Inferred from Electronic Annotation more info
enables exonuclease activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in nucleic acid metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Exonuclease domain-containing protein;putative oligoribonuclease

NP_001256185.1

Confirmed by transcript evidence

NP_001256186.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

10134643..10143014

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001269256.3 → NP_001256185.1 putative oligoribonuclease [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001256185.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q17819

Conserved Domains (1) summary

cd06135
Location:15 → 185

Orn; DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins
NM_001269257.3 → NP_001256186.1 Exonuclease domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001256186.1

Status: REVIEWED

UniProtKB/TrEMBL

G3MU09

Conserved Domains (1) summary

cl10012
Location:1 → 68

DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily