U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    F55H12.3 CUB domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172702, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    F55H12.3
    Official Full Name
    CUB domain-containing protein
    Primary source
    WormBase:WBGene00010134
    Locus tag
    CELE_F55H12.3
    See related
    AllianceGenome:WB:WBGene00010134
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable Notch binding activity. Predicted to be located in extracellular region and membrane. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See F55H12.3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    52
    Sequence:
    Chromosome: I; NC_003279.8 (8876319..8893317)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Tyrosine-protein phosphatase domain-containing protein Neighboring gene Transporter Neighboring gene DB domain-containing protein Neighboring gene Acetylcholine receptor subunit beta-type unc-29 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Epsin potentiates Notch pathway activity in Drosophila and C. elegans. Tian X, et al. Development, 2004 Dec. PMID 15539484
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables Notch binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    CUB domain-containing protein
    NP_492397.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8876319..8893317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059996.7 → NP_492397.4  CUB domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492397.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      P90891
      Conserved Domains (9) summary
      cd00033
      Location:1066 → 1110
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      smart00032
      Location:604 → 651
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      smart00179
      Location:851 → 884
      EGF_CA; Calcium-binding EGF-like domain
      cd00112
      Location:185 → 217
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cd00185
      Location:2530 → 2590
      TNFRSF; CRD2 [structural motif]
      pfam02494
      Location:2235 → 2315
      HYR; HYR domain
      pfam07699
      Location:2517 → 2567
      GCC2_GCC3; GCC2 and GCC3
      pfam07974
      Location:1869 → 1900
      EGF_2; EGF-like domain
      cl22855
      Location:2510 → 2657
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.