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    W08E12.7 Peptidase M24 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177097, updated on 9-Dec-2024

    Summary

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    Official Symbol
    W08E12.7
    Official Full Name
    Peptidase M24 domain-containing protein
    Primary source
    WormBase:WBGene00021088
    Locus tag
    CELE_W08E12.7
    See related
    AllianceGenome:WB:WBGene00021088
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in gonad; intestine; and pharynx. Orthologous to human PA2G4 (proliferation-associated 2G4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See W08E12.7 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (3295135..3297027)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Receptor-type guanylate cyclase gcy-23 Neighboring gene ncRNA Neighboring gene Protein Upregulated in Glial Subsets Neighboring gene Uncharacterized protein Neighboring gene CC domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification. Zhang C, et al. Curr Biol, 2012 May 22. PMID 22542102, Free PMC Article
    2. AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity. Ruiz M, et al. J Biol Chem, 2023 Jun. PMID 37164154, Free PMC Article
    3. CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing. Lugano DI, et al. RNA Biol, 2024 Jan. PMID 38126797, Free PMC Article
    4. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    Peptidase M24 domain-containing protein
    NP_500311.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3295135..3297027
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067910.9 → NP_500311.1  Peptidase M24 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500311.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N5B3
      Conserved Domains (1) summary
      cl00279
      Location:21 → 391
      APP_MetAP; A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity ...
    Nucleotide Protein
    Heading Accession and Version

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