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    sto-2 Stomatin-2 [ Caenorhabditis elegans ]

    Gene ID: 180802, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sto-2
    Official Full Name
    Stomatin-2
    Primary source
    WormBase:WBGene00006064
    Locus tag
    CELE_F32A6.5
    See related
    AllianceGenome:WB:WBGene00006064
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including STOM (stomatin). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sto-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Sequence:
    Chromosome: X; NC_003284.9 (5307486..5323387, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Activator of G protein signaling;TPR_REGION domain-containing protein;Tetratricopeptide repeat protein 28 Neighboring gene ncRNA Neighboring gene IFT81 calponin homology domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Phe Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Serine protease K12H4.7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of innate immunity genes and pathways using a comparative genomics approach. Alper S, et al. Proc Natl Acad Sci U S A, 2008 May 13. PMID 18463287, Free PMC Article
    2. Functional genomics of the cilium, a sensory organelle. Blacque OE, et al. Curr Biol, 2005 May 24. PMID 15916950
    3. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. Brinzer RA, et al. G3 (Bethesda), 2024 Mar 6. PMID 38227795, Free PMC Article
    4. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Stomatin-2
    NP_001257020.1
    • Confirmed by transcript evidence
    NP_001257021.1
    • Confirmed by transcript evidence
    NP_001257022.1
    • Confirmed by transcript evidence
    NP_001257023.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5307486..5323387 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001270092.5 → NP_001257021.1  Stomatin-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257021.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D5MCN3, D5MCN4, D5MCN5, D5MCN6, Q19958
      Conserved Domains (2) summary
      smart00244
      Location:146 → 298
      PHB; prohibitin homologues
      cl19107
      Location:168 → 368
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    2. NM_001270091.4 → NP_001257020.1  Stomatin-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257020.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19958
      Conserved Domains (2) summary
      smart00244
      Location:129 → 281
      PHB; prohibitin homologues
      cl19107
      Location:151 → 351
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    3. NM_001270094.2 → NP_001257023.1  Stomatin-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257023.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19958
      Conserved Domains (2) summary
      smart00244
      Location:91 → 243
      PHB; prohibitin homologues
      cl19107
      Location:113 → 313
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    4. NM_001270093.4 → NP_001257022.1  Stomatin-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257022.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19958
      Conserved Domains (2) summary
      smart00244
      Location:118 → 270
      PHB; prohibitin homologues
      cl19107
      Location:140 → 340
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q19958.4

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