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    K05F1.10 TIL domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 187030, updated on 9-Dec-2024

    Summary

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    Official Symbol
    K05F1.10
    Official Full Name
    TIL domain-containing protein
    Primary source
    WormBase:WBGene00019411
    Locus tag
    CELE_K05F1.10
    See related
    AllianceGenome:WB:WBGene00019411
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Involved in innate immune response. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See K05F1.10 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (5803675..5805473, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Col_cuticle_N domain-containing protein Neighboring gene Major sperm protein Neighboring gene protein of unknown function DX domain-containing protein Neighboring gene ncRNA Neighboring gene Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in innate immune response HEP PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    TIL domain-containing protein
    NP_001343656.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5803675..5805473 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356845.4 → NP_001343656.1  TIL domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21248
      Conserved Domains (1) summary
      pfam01826
      Location:53 → 115
      TIL; Trypsin Inhibitor like cysteine rich domain
    Nucleotide Protein
    Heading Accession and Version

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