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    Y50D7A.3 Protein kinase domain-containing protein;phosphorylase kinase [ Caenorhabditis elegans ]

    Gene ID: 190101, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y50D7A.3
    Official Full Name
    Protein kinase domain-containing protein;phosphorylase kinase
    Primary source
    WormBase:WBGene00021753
    Locus tag
    CELE_Y50D7A.3
    See related
    AllianceGenome:WB:WBGene00021753
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phosphorylase kinase activity. Predicted to be involved in glycogen metabolic process and signal transduction. Predicted to be part of phosphorylase kinase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease IXc; and liver cirrhosis. Orthologous to several human genes including PHKG2 (phosphorylase kinase catalytic subunit gamma 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y50D7A.3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (254535..264892)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene N-alpha-acetyltransferase 16, NatA auxiliary subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA 5'-3' helicase Neighboring gene ncRNA Neighboring gene Transcriptional regulatory protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphorylase kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphorylase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycogen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycogen metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glycogen metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of phosphorylase kinase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of phosphorylase kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein kinase domain-containing protein;phosphorylase kinase
    NP_001360127.1
    • Confirmed by transcript evidence
    NP_001368037.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      254535..264892
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381687.3 → NP_001368037.1  phosphorylase kinase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3L4
      Conserved Domains (1) summary
      cd14093
      Location:27 → 298
      STKc_PhKG; Catalytic domain of the Serine/Threonine Kinase, Phosphorylase kinase Gamma subunit

    2. NM_001373828.3 → NP_001360127.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0P0
      Conserved Domains (1) summary
      cl21453
      Location:27 → 97
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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