eng-1 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: eng-1
Official Full Name: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
Primary source: WormBase:WBGene00017164
Locus tag: CELE_F01F1.10
See related: AllianceGenome:WB:WBGene00017164
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Predicted to be involved in N-glycan processing. Predicted to be located in cytosol. Is expressed in pharyngeal cell. Orthologous to human ENGASE (endo-beta-N-acetylglucosaminidase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See eng-1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 6

Sequence:: Chromosome: III; NC_003281.10 (5866495..5868501, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

F01F1.10 (e-PCR)
- UniSTS:309545

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in N-glycan processing	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase

NP_001021238.1

Confirmed by transcript evidence

NP_001359901.1

Confirmed by transcript evidence

NP_498267.3

Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

5866495..5868501 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001026067.5 → NP_001021238.1 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001021238.1

Status: REVIEWED

UniProtKB/TrEMBL

Q8TA65

Conserved Domains (1) summary

cd06547
Location:41 → 373

GH85_ENGase; Endo-beta-N-acetylglucosaminidase (ENGase) hydrolyzes the N-N'-diacetylchitobiosyl core of N-glycosylproteins. The beta-1,4-glycosyl bond located between two N-acetylglucosamine residues is hydrolyzed such that N-acetylglucosamine 1 remains with the ...
NM_001372601.3 → NP_001359901.1 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q65ZJ9

Conserved Domains (1) summary

cd06547
Location:1 → 328

GH85_ENGase; Endo-beta-N-acetylglucosaminidase (ENGase) hydrolyzes the N-N'-diacetylchitobiosyl core of N-glycosylproteins. The beta-1,4-glycosyl bond located between two N-acetylglucosamine residues is hydrolyzed such that N-acetylglucosamine 1 remains with the ...
NM_065866.6 → NP_498267.3 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498267.3

Status: REVIEWED

UniProtKB/TrEMBL

Q19089

Conserved Domains (1) summary

cd06547
Location:41 → 288

GH85_ENGase; Endo-beta-N-acetylglucosaminidase (ENGase) hydrolyzes the N-N'-diacetylchitobiosyl core of N-glycosylproteins. The beta-1,4-glycosyl bond located between two N-acetylglucosamine residues is hydrolyzed such that N-acetylglucosamine 1 remains with the ...