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    mrpl-50 Large ribosomal subunit protein mL50 [ Caenorhabditis elegans ]

    Gene ID: 174422, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mrpl-50
    Official Full Name
    Large ribosomal subunit protein mL50
    Primary source
    WormBase:WBGene00011883
    Locus tag
    CELE_T21B10.1
    See related
    AllianceGenome:WB:WBGene00011883
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL50 (mitochondrial ribosomal protein L50). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mrpl-50 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (8929841..8930940)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Glycine-rich protein Neighboring gene ncRNA Neighboring gene T-complex protein 1 subunit beta Neighboring gene Enolase Neighboring gene THO complex subunit 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lifespan regulation by evolutionarily conserved genes essential for viability. Curran SP, et al. PLoS Genet, 2007 Apr 6. PMID 17411345, Free PMC Article
    2. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Large ribosomal subunit protein mL50
    NP_495899.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8929841..8930940
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063498.6 → NP_495899.1  Large ribosomal subunit protein mL50 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495899.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22623
      Conserved Domains (1) summary
      pfam10501
      Location:92 → 194
      Ribosomal_L50; Ribosomal subunit 39S
    Nucleotide Protein
    Heading Accession and Version

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