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    trpl-2 Ion_trans domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177198, updated on 9-Dec-2024

    Summary

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    Official Symbol
    trpl-2
    Official Full Name
    Ion_trans domain-containing protein
    Primary source
    WormBase:WBGene00020972
    Locus tag
    CELE_W03B1.2
    See related
    AllianceGenome:WB:WBGene00020972
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable monoatomic cation channel activity. Predicted to be involved in metal ion transport and monoatomic cation transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See trpl-2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    12
    Sequence:
    Chromosome: IV; NC_003282.8 (4326654..4332083)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene BAR domain-containing protein Neighboring gene pseudo Neighboring gene Acyl_transf_3 domain-containing protein;SGNH domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Heat avoidance is regulated by transient receptor potential (TRP) channels and a neuropeptide signaling pathway in Caenorhabditis elegans. Glauser DA, et al. Genetics, 2011 May. PMID 21368276, Free PMC Article
    2. Mechanosensation. Goodman MB. WormBook, 2006 Jan 6. PMID 18050466, Free PMC Article
    3. A database of Caenorhabditis elegans behavioral phenotypes. Yemini E, et al. Nat Methods, 2013 Sep. PMID 23852451, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables monoatomic cation channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in metal ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in monoatomic cation transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Ion_trans domain-containing protein
    NP_500541.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      4326654..4332083
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068140.4 → NP_500541.2  Ion_trans domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500541.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23141
      Conserved Domains (1) summary
      TIGR00870
      Location:447 → 677
      trp; transient-receptor-potential calcium channel protein
    Nucleotide Protein
    Heading Accession and Version

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