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    pals-5 Protein containing ALS2cr12 (ALS2CR12) signature [ Caenorhabditis elegans ]

    Gene ID: 182748, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pals-5
    Official Full Name
    Protein containing ALS2cr12 (ALS2CR12) signature
    Primary source
    WormBase:WBGene00007659
    Locus tag
    CELE_C17H1.6
    See related
    AllianceGenome:WB:WBGene00007659
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in innate immune response. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pals-5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (13130813..13132466, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Protein containing ALS2cr12 (ALS2CR12) signature Neighboring gene ncRNA Neighboring gene Protein containing ALS2cr12 (ALS2CR12) signature Neighboring gene Protein containing ALS2cr12 (ALS2CR12) signature

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nanoluciferase-Based Method for Detecting Gene Expression in Caenorhabditis elegans. Sfarcic I, et al. Genetics, 2019 Dec. PMID 31585955, Free PMC Article
    2. Balancing Selection of the Intracellular Pathogen Response in Natural Caenorhabditis elegans Populations. van Sluijs L, et al. Front Cell Infect Microbiol, 2021. PMID 35174100, Free PMC Article
    3. Ubiquitin-mediated response to microsporidia and virus infection in C. elegans. Bakowski MA, et al. PLoS Pathog, 2014 Jun. PMID 24945527, Free PMC Article
    4. A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans. Gang SS, et al. PLoS Genet, 2022 Oct. PMID 36191002, Free PMC Article
    5. Proteasome inhibition triggers tissue-specific immune responses against different pathogens in C. elegans. Grover M, et al. PLoS Biol, 2024 Mar. PMID 38466732, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in innate immune response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Protein containing ALS2cr12 (ALS2CR12) signature
    NP_493300.1
    • Product from WormBase gene class pals;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      13130813..13132466 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060899.6 → NP_493300.1  Protein containing ALS2cr12 (ALS2CR12) signature [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493300.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45257
    Nucleotide Protein
    Heading Accession and Version

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