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    C27C7.5 Galectin [ Caenorhabditis elegans ]

    Gene ID: 182958, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C27C7.5
    Official Full Name
    Galectin
    Primary source
    WormBase:WBGene00007768
    Locus tag
    CELE_C27C7.5
    See related
    AllianceGenome:WB:WBGene00007768
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable carbohydrate binding activity and galactoside binding activity. Orthologous to several human genes including CLC (Charcot-Leyden crystal galectin); LGALS12 (galectin 12); and LGALS13 (galectin 13). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C27C7.5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (11423993..11426054, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene protein of unknown function WSN domain-containing protein Neighboring gene RING-type E3 ubiquitin transferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nuclear receptor domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables galactoside binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Galectin
    NP_001263496.1
    • Partially confirmed by transcript evidence
    NP_492918.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      11423993..11426054 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001276567.2 → NP_001263496.1  Galectin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263496.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8ERT0
      Conserved Domains (2) summary
      smart00605
      Location:17 → 109
      CW; CW domain
      pfam00337
      Location:149 → 271
      Gal-bind_lectin; Galactoside-binding lectin

    2. NM_060517.6 → NP_492918.2  Galectin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492918.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XVD0
      Conserved Domains (2) summary
      smart00605
      Location:1 → 91
      CW; CW domain
      cd00070
      Location:131 → 258
      GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...
    Nucleotide Protein
    Heading Accession and Version

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