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    cfap-36 Cilia- and flagella-associated protein 36 [ Caenorhabditis elegans ]

    Gene ID: 190931, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cfap-36
    Official Full Name
    Cilia- and flagella-associated protein 36
    Primary source
    WormBase:WBGene00022435
    Locus tag
    CELE_Y108G3AL.3
    See related
    AllianceGenome:WB:WBGene00022435
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in axoneme and ciliary base. Is expressed in ciliated neurons. Orthologous to human CFAP36 (cilia and flagella associated protein 36). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cfap-36 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (163842..172210, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class H Neighboring gene Choline/carnitine acyltransferase domain-containing protein Neighboring gene Transcription initiation factor IIB Neighboring gene Pre-mRNA-splicing factor 38 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport. Jensen VL, et al. PLoS Genet, 2016 Dec. PMID 27930654, Free PMC Article
    2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in axoneme IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in axoneme IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in ciliary base IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ciliary base IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cilia- and flagella-associated protein 36
    NP_001300217.1
    • Confirmed by transcript evidence
    NP_503147.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      163842..172210 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070746.6 → NP_503147.1  Cilia- and flagella-associated protein 36 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503147.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0K3ASD3, Q95Y36
      Conserved Domains (2) summary
      pfam11527
      Location:31 → 136
      ARL2_Bind_BART; The ARF-like 2 binding protein BART
      cl28033
      Location:289 → 546
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    2. NM_001313288.3 → NP_001300217.1  Cilia- and flagella-associated protein 36 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95Y36
      Conserved Domains (1) summary
      PHA03307
      Location:162 → 419
      PHA03307; transcriptional regulator ICP4; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95Y36.1

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