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    cest-26 Carboxylic ester hydrolase [ Caenorhabditis elegans ]

    Gene ID: 180715, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cest-26
    Official Full Name
    Carboxylic ester hydrolase
    Primary source
    WormBase:WBGene00017478
    Locus tag
    CELE_F15A8.6
    See related
    AllianceGenome:WB:WBGene00017478
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable carboxylic ester hydrolase activity. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cest-26 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Sequence:
    Chromosome: X; NC_003284.9 (4430862..4437655, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene UMA domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables carboxylic ester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Carboxylic ester hydrolase
    NP_001367709.1
    • Confirmed by transcript evidence
    NP_001368609.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      4430862..4437655 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001380948.2 → NP_001367709.1  Carboxylic ester hydrolase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O02147
      Conserved Domains (1) summary
      pfam00135
      Location:20 → 555
      COesterase; Carboxylesterase family

    2. NM_001380947.1 → NP_001368609.1  Carboxylic ester hydrolase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1C3NSL8
      Conserved Domains (1) summary
      pfam00135
      Location:40 → 575
      COesterase; Carboxylesterase family
    Nucleotide Protein
    Heading Accession and Version

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