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    T28D6.6 GTP-binding protein 128up;OBG-type G domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176563, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T28D6.6
    Official Full Name
    GTP-binding protein 128up;OBG-type G domain-containing protein
    Primary source
    WormBase:WBGene00012126
    Locus tag
    CELE_T28D6.6
    See related
    AllianceGenome:WB:WBGene00012126
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable GTP binding activity. Predicted to be involved in cytoplasmic translation. Predicted to be active in cytoplasm. Orthologous to human DRG1 (developmentally regulated GTP binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T28D6.6 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (11326654..11343108, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Ras-related protein Rab-35 Neighboring gene GYF domain-containing protein Neighboring gene Protein MCM10 homolog Neighboring gene CUB domain-containing protein Neighboring gene START domain-containing protein Neighboring gene Gamma-secretase subunit pen-2 Neighboring gene tRNA-Val

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    2. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    3. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    4. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GTP-binding protein 128up;OBG-type G domain-containing protein
    NP_001255120.1
    • Confirmed by transcript evidence
    NP_001255126.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      11326654..11343108 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268197.2 → NP_001255126.1  GTP-binding protein 128up [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255126.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EGL2
      Conserved Domains (1) summary
      COG1163
      Location:1 → 365
      Rbg1; Ribosome-interacting GTPase 1 [Translation, ribosomal structure and biogenesis]

    2. NM_001268191.3 → NP_001255120.1  OBG-type G domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255120.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G2HK05
      Conserved Domains (1) summary
      COG1163
      Location:1 → 221
      Rbg1; Ribosome-interacting GTPase 1 [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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