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    Rabepk Rab9 effector protein with kelch motifs [ Mus musculus (house mouse) ]

    Gene ID: 227746, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rabepkprovided by MGI
    Official Full Name
    Rab9 effector protein with kelch motifsprovided by MGI
    Primary source
    MGI:MGI:2139530
    See related
    Ensembl:ENSMUSG00000070953 AllianceGenome:MGI:2139530
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rab9p40; 8430412M01Rik; 9530020D24Rik
    Summary
    Predicted to be located in intracellular membrane-bounded organelle. Is expressed in embryo. Orthologous to human RABEPK (Rab9 effector protein with kelch motifs). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in testis adult (RPKM 48.4), genital fat pad adult (RPKM 5.2) and 18 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rabepk in Genome Data Viewer
    Location:
    2 B; 2 22.94 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (34662946..34690200, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (34774609..34800196, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 34372 Neighboring gene DnaJ (Hsp40) homolog, subfamily B, member 6 pseudogene Neighboring gene GTPase activating protein and VPS9 domains 1 Neighboring gene STARR-seq mESC enhancer starr_04265 Neighboring gene heat shock protein 5 Neighboring gene predicted gene, 53241 Neighboring gene STARR-seq mESC enhancer starr_04266 Neighboring gene STARR-seq mESC enhancer starr_04267 Neighboring gene F-box and WD-40 domain protein 2 Neighboring gene STARR-seq mESC enhancer starr_04268 Neighboring gene beta-1,3-galactosyltransferase 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in endosome membrane  
    located_in intracellular membrane-bounded organelle  

    General protein information

    Preferred Names
    rab9 effector protein with kelch motifs
    Names
    Rab9 effector p40

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374669.1NP_001361598.1  rab9 effector protein with kelch motifs isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL929106
      Consensus CDS
      CCDS89479.1
      UniProtKB/TrEMBL
      A2AUF7, B0R0S4
      Related
      ENSMUSP00000113099.2, ENSMUST00000118108.2
      Conserved Domains (4) summary
      PLN02193
      Location:126294
      PLN02193; nitrile-specifier protein
      sd00038
      Location:86135
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:3082
      Kelch_2; Kelch motif
      pfam13415
      Location:99147
      Kelch_3; Galactose oxidase, central domain
    2. NM_145522.4NP_663497.2  rab9 effector protein with kelch motifs isoform 1

      See identical proteins and their annotated locations for NP_663497.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK035343, AL929106
      Consensus CDS
      CCDS15951.1
      UniProtKB/Swiss-Prot
      Q8BZG7, Q8VCH5
      UniProtKB/TrEMBL
      A2AUF7
      Related
      ENSMUSP00000122360.2, ENSMUST00000145903.8
      Conserved Domains (4) summary
      PLN02193
      Location:134302
      PLN02193; nitrile-specifier protein
      sd00038
      Location:94143
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:3890
      Kelch_2; Kelch motif
      pfam13415
      Location:107155
      Kelch_3; Galactose oxidase, central domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      34662946..34690200 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160906.1XP_036016799.1  rab9 effector protein with kelch motifs isoform X6

      Conserved Domains (4) summary
      PLN02193
      Location:133283
      PLN02193; nitrile-specifier protein
      sd00038
      Location:94142
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:3888
      Kelch_2; Kelch motif
      pfam13415
      Location:107154
      Kelch_3; Galactose oxidase, central domain
    2. XM_017317453.3XP_017172942.1  rab9 effector protein with kelch motifs isoform X5

      Conserved Domains (4) summary
      PLN02193
      Location:134284
      PLN02193; nitrile-specifier protein
      sd00038
      Location:94143
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:3890
      Kelch_2; Kelch motif
      pfam13415
      Location:107155
      Kelch_3; Galactose oxidase, central domain
    3. XM_036160907.1XP_036016800.1  rab9 effector protein with kelch motifs isoform X7

      Conserved Domains (4) summary
      PLN02193
      Location:126276
      PLN02193; nitrile-specifier protein
      sd00038
      Location:86135
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:3080
      Kelch_2; Kelch motif
      pfam13415
      Location:99147
      Kelch_3; Galactose oxidase, central domain
    4. XM_030250015.2XP_030105875.1  rab9 effector protein with kelch motifs isoform X2

      UniProtKB/TrEMBL
      A2AUF7
      Conserved Domains (4) summary
      PLN02193
      Location:125293
      PLN02193; nitrile-specifier protein
      sd00038
      Location:86134
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:3082
      Kelch_2; Kelch motif
      pfam13415
      Location:99146
      Kelch_3; Galactose oxidase, central domain
    5. XM_030250020.2XP_030105880.1  rab9 effector protein with kelch motifs isoform X4

      Conserved Domains (3) summary
      PLN02193
      Location:58226
      PLN02193; nitrile-specifier protein
      sd00038
      Location:1967
      Kelch; KELCH repeat [structural motif]
      pfam13415
      Location:3279
      Kelch_3; Galactose oxidase, central domain
    6. XM_006497987.5XP_006498050.1  rab9 effector protein with kelch motifs isoform X3

      See identical proteins and their annotated locations for XP_006498050.1

      Conserved Domains (3) summary
      PLN02193
      Location:59227
      PLN02193; nitrile-specifier protein
      sd00038
      Location:1968
      Kelch; KELCH repeat [structural motif]
      pfam13415
      Location:3280
      Kelch_3; Galactose oxidase, central domain
    7. XM_006497989.4XP_006498052.1  rab9 effector protein with kelch motifs isoform X9

      Conserved Domains (2) summary
      PLN02193
      Location:7175
      PLN02193; nitrile-specifier protein
      sd00038
      Location:2070
      Kelch; KELCH repeat [structural motif]
    8. XM_030250025.2XP_030105885.1  rab9 effector protein with kelch motifs isoform X8

      Conserved Domains (2) summary
      PLN02193
      Location:8176
      PLN02193; nitrile-specifier protein
      sd00038
      Location:2172
      Kelch; KELCH repeat [structural motif]
    9. XM_006497984.5XP_006498047.1  rab9 effector protein with kelch motifs isoform X1

      UniProtKB/TrEMBL
      A2AUF7
      Conserved Domains (4) summary
      PLN02193
      Location:133301
      PLN02193; nitrile-specifier protein
      sd00038
      Location:94142
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:3890
      Kelch_2; Kelch motif
      pfam13415
      Location:107154
      Kelch_3; Galactose oxidase, central domain
    10. XM_030250019.2XP_030105879.1  rab9 effector protein with kelch motifs isoform X4

      Conserved Domains (3) summary
      PLN02193
      Location:58226
      PLN02193; nitrile-specifier protein
      sd00038
      Location:1967
      Kelch; KELCH repeat [structural motif]
      pfam13415
      Location:3279
      Kelch_3; Galactose oxidase, central domain
    11. XM_006497986.4XP_006498049.1  rab9 effector protein with kelch motifs isoform X3

      See identical proteins and their annotated locations for XP_006498049.1

      Conserved Domains (3) summary
      PLN02193
      Location:59227
      PLN02193; nitrile-specifier protein
      sd00038
      Location:1968
      Kelch; KELCH repeat [structural motif]
      pfam13415
      Location:3280
      Kelch_3; Galactose oxidase, central domain
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