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    Idi2 isopentenyl-diphosphate delta isomerase 2 [ Mus musculus (house mouse) ]

    Gene ID: 320581, updated on 9-Dec-2024

    Summary

    Official Symbol
    Idi2provided by MGI
    Official Full Name
    isopentenyl-diphosphate delta isomerase 2provided by MGI
    Primary source
    MGI:MGI:2444315
    See related
    Ensembl:ENSMUSG00000033520 AllianceGenome:MGI:2444315
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    IPPI2; 4833405L16Rik
    Summary
    Predicted to enable isopentenyl-diphosphate delta-isomerase activity. Acts upstream of or within negative regulation of cholesterol biosynthetic process. Predicted to be located in peroxisome. Predicted to be active in cytoplasm. Orthologous to human IDI2 (isopentenyl-diphosphate delta isomerase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Idi2 in Genome Data Viewer
    Location:
    13 A1; 13 3.63 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (9002899..9010981)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (8952863..8960935)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene isopentenyl-diphosphate delta isomerase 2 like Neighboring gene predicted gene, 25274 Neighboring gene predicted gene, 22115 Neighboring gene predicted gene, 23923 Neighboring gene GTP binding protein 4 Neighboring gene STARR-positive B cell enhancer ABC_E2396 Neighboring gene predicted gene, 36264 Neighboring gene ribosomal protein S2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in cytoplasm  
    located_in intracellular membrane-bounded organelle  
    located_in peroxisome  

    General protein information

    Preferred Names
    isopentenyl-diphosphate delta-isomerase 2
    Names
    IPP isomerase 2
    isopentenyl diphosphate delta-isomerase type 2
    isopentenyl pyrophosphate isomerase 2
    isopentenyl-diphosphate Delta-isomerase 2
    NP_796171.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177197.5 → NP_796171.1  isopentenyl-diphosphate delta-isomerase 2

      See identical proteins and their annotated locations for NP_796171.1

      Status: VALIDATED

      Source sequence(s)
      AC124732
      Consensus CDS
      CCDS26235.1
      UniProtKB/Swiss-Prot
      Q4FZF0, Q8BFZ6
      Related
      ENSMUSP00000036621.2, ENSMUST00000038598.3
      Conserved Domains (2) summary
      COG1443
      Location:18 → 215
      Idi; Isopentenyldiphosphate isomerase [Lipid transport and metabolism]
      cl00447
      Location:18 → 227
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      9002899..9010981
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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