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    Secisbp2l SECIS binding protein 2-like [ Mus musculus (house mouse) ]

    Gene ID: 70354, updated on 9-Dec-2024

    Summary

    Official Symbol
    Secisbp2lprovided by MGI
    Official Full Name
    SECIS binding protein 2-likeprovided by MGI
    Primary source
    MGI:MGI:1917604
    See related
    Ensembl:ENSMUSG00000035093 AllianceGenome:MGI:1917604
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C630011I23; 3110001I20Rik
    Summary
    Predicted to enable mRNA 3'-UTR binding activity and ribonucleoprotein complex binding activity. Predicted to be part of ribonucleoprotein complex. Predicted to be active in mitochondrion. Orthologous to human SECISBP2L (SECIS binding protein 2 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in lung adult (RPKM 11.1), cerebellum adult (RPKM 8.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Secisbp2l in Genome Data Viewer
    Location:
    2 F1; 2 61.76 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (125578906..125624790, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (125736986..125782870, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene SHC (Src homology 2 domain containing) family, member 4 Neighboring gene STARR-seq mESC enhancer starr_05593 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:125550365-125550474 Neighboring gene predicted gene, 35231 Neighboring gene EP300 interacting inhibitor of differentiation 1 Neighboring gene STARR-positive B cell enhancer ABC_E11155 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:125602741-125602942 Neighboring gene STARR-positive B cell enhancer ABC_E5976 Neighboring gene STARR-positive B cell enhancer ABC_E7857 Neighboring gene STARR-positive B cell enhancer ABC_E11156 Neighboring gene COP9 signalosome subunit 2 Neighboring gene galactokinase 2 Neighboring gene family with sequence similarity 227, member B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1)  1 citation

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mRNA 3'-UTR binding  
    enables ribonucleoprotein complex binding  
    enables selenocysteine insertion sequence binding  
    Component Evidence Code Pubs
    is_active_in mitochondrion  
    part_of ribonucleoprotein complex  

    General protein information

    Preferred Names
    selenocysteine insertion sequence-binding protein 2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001369056.1NP_001355985.1  selenocysteine insertion sequence-binding protein 2-like isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL844580
      Conserved Domains (1) summary
      pfam01248
      Location:377479
      Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
    2. NM_177608.3NP_808276.2  selenocysteine insertion sequence-binding protein 2-like isoform 2

      See identical proteins and their annotated locations for NP_808276.2

      Status: VALIDATED

      Source sequence(s)
      AK049924, AL844580, CB289930, CB528069, CJ198024
      Consensus CDS
      CCDS38230.1
      UniProtKB/Swiss-Prot
      Q6A098
      UniProtKB/TrEMBL
      A2AQE2
      Related
      ENSMUSP00000055772.7, ENSMUST00000053699.13
      Conserved Domains (1) summary
      pfam01248
      Location:700802
      Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      125578906..125624790 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500156.5XP_006500219.1  selenocysteine insertion sequence-binding protein 2-like isoform X1

      UniProtKB/Swiss-Prot
      Q6A098
      Conserved Domains (1) summary
      pfam01248
      Location:589691
      Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

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