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    Evi2 ecotropic viral integration site 2 [ Mus musculus (house mouse) ]

    Gene ID: 101488212, updated on 9-Dec-2024

    Summary

    Official Symbol
    Evi2provided by MGI
    Official Full Name
    ecotropic viral integration site 2provided by MGI
    Primary source
    MGI:MGI:5439444
    See related
    AllianceGenome:MGI:5439444
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm21975; Evi2a-evi2b
    Summary
    This locus represents naturally occurring readthrough transcription between the neighboring Evi2a (ecotropic viral integration site 2a) and Evi2b (ecotropic viral integration site 2b) genes on chromosome 11. The readthrough transcript encodes a protein identical to that of the downstream gene product. [provided by RefSeq, May 2013]
    Expression
    Broad expression in spleen adult (RPKM 20.8), thymus adult (RPKM 14.9) and 18 other tissues See more
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    Genomic context

    See Evi2 in Genome Data Viewer
    Location:
    11 B5; 11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (79404211..79421435, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (79513385..79530609, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene neurofibromin 1 Neighboring gene STARR-seq mESC enhancer starr_30120 Neighboring gene expressed sequence AU040972 Neighboring gene STARR-positive B cell enhancer ABC_E8431 Neighboring gene STARR-positive B cell enhancer ABC_E7024 Neighboring gene STARR-positive B cell enhancer ABC_E5254 Neighboring gene STARR-positive B cell enhancer ABC_E11485 Neighboring gene oligodendrocyte myelin glycoprotein Neighboring gene ecotropic viral integration site 2b Neighboring gene ecotropic viral integration site 2a Neighboring gene STARR-positive B cell enhancer ABC_E11768 Neighboring gene RAB11 family interacting protein 4 (class II) Neighboring gene RAB11 family interacting protein 4 (class II), opposite strand 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:79428461-79428644 Neighboring gene predicted gene, 23293

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Readthrough Evi2

    Included genes: Evi2a, Evi2b

    General protein information

    Preferred Names
    protein EVI2B
    Names
    Evi2a-Evi2b readthrough
    ecotropic viral integration site 2B protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146023.4NP_666135.1  protein EVI2B precursor

      See identical proteins and their annotated locations for NP_666135.1

      Status: VALIDATED

      Source sequence(s)
      AK034440, AL591174
      UniProtKB/Swiss-Prot
      Q3U1A3, Q8VD58
      Conserved Domains (1) summary
      PRK13335
      Location:32169
      PRK13335; superantigen-like protein; Reviewed

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      79404211..79421435 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)