Zfp963 zinc finger protein 963 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp963provided by MGI
Official Full Name: zinc finger protein 963provided by MGI
Primary source: MGI:MGI:4867078
See related: Ensembl:ENSMUSG00000092260 AllianceGenome:MGI:4867078
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF669 (zinc finger protein 669). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in CNS E14 (RPKM 3.7), CNS E11.5 (RPKM 3.5) and 28 other tissues See more
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Genomic context

Location:: 8 B3.3; 8 33.88 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (70194289..70202612, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (69741639..69749962, complement)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AI875089 (e-PCR)
- UniSTS:179752

NoName (e-PCR)
- UniSTS:235910

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: zinc finger protein 669-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001200023.1 → NP_001186952.1 zinc finger protein 669-like

Status: VALIDATED

Source sequence(s)

AC157564, AK162670

Consensus CDS

CCDS52566.1

UniProtKB/TrEMBL

D3Z2T8

Related

ENSMUSP00000119087.2, ENSMUST00000130458.8

Conserved Domains (5) summary

smart00349
Location:4 → 44

KRAB; krueppel associated box

COG5048
Location:185 → 383

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:298 → 318

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:4 → 41

KRAB; KRAB box

pfam13465
Location:338 → 363

zf-H2C2_2; Zinc-finger double domain