Dnajc16 DnaJ heat shock protein family (Hsp40) member C16 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Dnajc16provided by MGI
Official Full Name: DnaJ heat shock protein family (Hsp40) member C16provided by MGI
Primary source: MGI:MGI:2442146
See related: Ensembl:ENSMUSG00000040697 AllianceGenome:MGI:2442146
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: ERdj8; mKIAA0962; D030060M24; 2900037O03Rik; 4732437J24Rik
Summary: Predicted to be involved in regulation of autophagosome size. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human DNAJC16 (DnaJ heat shock protein family (Hsp40) member C16). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in ovary adult (RPKM 8.9), adrenal adult (RPKM 8.8) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 4 D3; 4 74.75 cM

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (141487498..141518255, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (141761998..141790644, complement)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in regulation of autophagosome size	ISO Inferred from Sequence Orthology more info
involved_in regulation of autophagosome size	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: dnaJ homolog subfamily C member 16

Names: DnaJ (Hsp40) homolog, subfamily C, member 16; ER-resident protein ERdj8; endoplasmic reticulum DNA J domain-containing protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_172338.2 → NP_758841.1 dnaJ homolog subfamily C member 16 precursor

See identical proteins and their annotated locations for NP_758841.1

Status: PROVISIONAL

Source sequence(s)

AL928577

Consensus CDS

CCDS18882.1

UniProtKB/Swiss-Prot

Q80TN4, Q811G1, Q8BHI2

Related

ENSMUSP00000048714.5, ENSMUST00000038014.11

Conserved Domains (2) summary

COG0484
Location:29 → 135

DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]

cd02963
Location:134 → 243

TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000070.7 Reference GRCm39 C57BL/6J

Range

141487498..141518255 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036163946.1 → XP_036019839.1 dnaJ homolog subfamily C member 16 isoform X1

UniProtKB/Swiss-Prot

Q80TN4, Q811G1, Q8BHI2

Conserved Domains (2) summary

COG0484
Location:29 → 135

DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]

cd02963
Location:134 → 243

TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...