Or2a7 olfactory receptor family 2 subfamily A member 7 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Or2a7provided by MGI
Official Full Name: olfactory receptor family 2 subfamily A member 7provided by MGI
Primary source: MGI:MGI:104812
See related: Ensembl:ENSMUSG00000043605 AllianceGenome:MGI:104812
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: K7; Olfr13; MOR261-6
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Orthologs: human all
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Genomic context

Location:: 6 B2.1; 6 21.1 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	6	NC_000072.7 (43150922..43151854)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	6	NC_000072.6 (43173988..43174920)

Chromosome 6 - NC_000072.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:492687

D1S3696 (e-PCR)
- UniSTS:474274

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	ISO Inferred from Sequence Orthology more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	ISO Inferred from Sequence Orthology more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of smell	IBA Inferred from Biological aspect of Ancestor more info
involved_in detection of chemical stimulus involved in sensory perception of smell	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sensory perception of smell	ISO Inferred from Sequence Orthology more info	PubMed

Component	Evidence Code	Pubs
located_in Flemming body	ISO Inferred from Sequence Orthology more info
located_in cleavage furrow	ISO Inferred from Sequence Orthology more info
located_in membrane	ISO Inferred from Sequence Orthology more info	PubMed
located_in mitotic spindle midzone	ISO Inferred from Sequence Orthology more info
located_in mitotic spindle pole	ISO Inferred from Sequence Orthology more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in recycling endosome	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: olfactory receptor 2A7

Names: GA_x6K02T2P3E9-4384160-4383228; odorant receptor K7; olfactory receptor 13; olfactory receptor 261-6; olfactory receptor MOR261-6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_146652.1 → NP_666863.1 olfactory receptor 2A7

See identical proteins and their annotated locations for NP_666863.1

Status: PROVISIONAL

Source sequence(s)

AY073444

Consensus CDS

CCDS20089.1

UniProtKB/Swiss-Prot

P34984, Q8VFS2

UniProtKB/TrEMBL

Q0VAZ7

Related

ENSMUSP00000053813.5, ENSMUST00000059512.5

Conserved Domains (2) summary

pfam00001
Location:40 → 289

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:30 → 304

7tm_4; Olfactory receptor