Fbxw7as1 F-box and WD-40 domain protein 7 antisense transcript 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Fbxw7as1provided by MGI
Official Full Name: F-box and WD-40 domain protein 7 antisense transcript 1provided by MGI
Primary source: MGI:MGI:3614654
See related: AllianceGenome:MGI:3614654
Gene type: ncRNA
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Dear; Dear1; Despr
Summary: Enables endothelin receptor activity; vascular endothelial growth factor binding activity; and vascular endothelial growth factor receptor activity. Acts upstream of or within several processes, including hippocampus development; learning or memory; and regulation of autophagy. Located in membrane. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; spleen; and yolk sac. [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: Note: The ncRNA locus type is based on analysis of mouse genome sequence data and normal tissue RNAseq samples. A report analyzing human cancer cell lines suggests there may be protein-coding potential in some circumstances (PMID:17446437, PMID:27301377). [13 Dec 2016]; not in current annotation release
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Alleles of this type are documented at Mouse Genome Informatics (MGI)

Function	Evidence Code	Pubs
enables endothelin receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables vascular endothelial growth factor binding	IDA Inferred from Direct Assay more info	PubMed
enables vascular endothelial growth factor receptor activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within blood vessel development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in endothelin receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within hippocampus development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within learning or memory	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of autophagy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vascular endothelial growth factor signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

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The following Reference Sequences have been suppressed. Explain

NM_001040461.2: Suppressed sequence

Description

NM_001040461.2: This RefSeq was removed because it is now thought that this gene does not encode a protein.