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    ldrD small toxic polypeptide LdrD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 2847730, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ldrD
    Official Full Name
    small toxic polypeptide LdrD
    Primary source
    ECOCYC:G0-9041
    Locus tag
    b4453
    See related
    ASAP:ABE-0047284
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3524
    Summary
    ldrD is one of a set of four Long Direct Repeats (LDRs), and has been shown to code for the toxin portion of a toxin-antitoxin pair. [More information is available at EcoCyc: G0-9041].
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    Genomic context

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    Sequence:
    NC_000913.3 (3699980..3700087, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene c-di-GMP-binding protein BcsE Neighboring gene putative cellulose biosynthesis protein BcsF Neighboring gene cellulose phosphoethanolamine transferase Neighboring gene ncRNA Neighboring gene putative transporter YhjV

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distribution of repetitive sequences on the leading and lagging strands of the Escherichia coli genome: comparative study of Long Direct Repeat (LDR) sequences. Kawano M, et al. DNA Res, 2002 Feb 28. PMID 11939563
    2. Hydrophobic peptides: novel regulators within bacterial membrane. Alix E, et al. Mol Microbiol, 2009 Apr. PMID 19210615
    3. Molecular characterization of long direct repeat (LDR) sequences expressing a stable mRNA encoding for a 35-amino-acid cell-killing peptide and a cis-encoded small antisense RNA in Escherichia coli. Kawano M, et al. Mol Microbiol, 2002 Jul. PMID 12123448
    4. Repression of small toxic protein synthesis by the Sib and OhsC small RNAs. Fozo EM, et al. Mol Microbiol, 2008 Dec. PMID 18710431, Free PMC Article
    5. Membranome: a database for proteome-wide analysis of single-pass membrane proteins. Lomize AL, et al. Nucleic Acids Res, 2017 Jan 4. PMID 27510400, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small toxic polypeptide LdrD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3699980..3700087 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026227.1 small toxic polypeptide LdrD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026227.1

      Status: PROVISIONAL

      Conserved Domains (1) summary
      pfam13940
      Location:1 → 35
      Ldr_toxin; Toxin Ldr, type I toxin-antitoxin system
    Nucleotide Protein
    Heading Accession and Version

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