Wdr17 WD repeat domain 17 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Wdr17provided by MGI
Official Full Name: WD repeat domain 17provided by MGI
Primary source: MGI:MGI:1924662
See related: Ensembl:ENSMUSG00000039375 AllianceGenome:MGI:1924662
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 3010002I12Rik; B230207L18Rik
Summary: Is expressed in brain; cortical plate; eye; olfactory epithelium; and spinal cord. Orthologous to human WDR17 (WD repeat domain 17). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in CNS E18 (RPKM 3.3), cortex adult (RPKM 3.0) and 6 other tissues See more
Orthologs: human all
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Genomic context

Location:: 8 B1.3; 8 29.28 cM

Exon count:: 35

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (55082316..55180014, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (54629281..54726979, complement)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Wdr17 (e-PCR), detects polymorphism
- UniSTS:255287

G65596 (e-PCR)
- UniSTS:225530

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

General protein information

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Preferred Names: WD repeat-containing protein 17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001172152.2 → NP_001165623.1 WD repeat-containing protein 17 isoform 2

See identical proteins and their annotated locations for NP_001165623.1

Status: VALIDATED

Source sequence(s)

AC102933, AC109200

Consensus CDS

CCDS52551.1

UniProtKB/TrEMBL

Q8C8Y2, Q8CFX0

Related

ENSMUSP00000122326.2, ENSMUST00000150488.8

Conserved Domains (3) summary

cd00200
Location:367 → 657

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:333 → 367

7WD40; WD40 repeat [structural motif]

cl29593
Location:51 → 441

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001364215.2 → NP_001351144.1 WD repeat-containing protein 17 isoform 3

Status: VALIDATED

Source sequence(s)

AC102933, AC109200

UniProtKB/TrEMBL

Q8CFX0

Conserved Domains (3) summary

cd00200
Location:293 → 583

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:259 → 293

7WD40; WD40 repeat [structural motif]

cl29593
Location:90 → 405

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001372370.1 → NP_001359299.1 WD repeat-containing protein 17 isoform 4

Status: VALIDATED

Source sequence(s)

AC102933, AC109200

UniProtKB/TrEMBL

E9Q271

Conserved Domains (3) summary

cd00200
Location:391 → 681

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:357 → 391

7WD40; WD40 repeat [structural motif]

cl29593
Location:75 → 465

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001372371.1 → NP_001359300.1 WD repeat-containing protein 17 isoform 4

Status: VALIDATED

Source sequence(s)

AC102933, AC109200

UniProtKB/TrEMBL

E9Q271

Conserved Domains (3) summary

cd00200
Location:391 → 681

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:357 → 391

7WD40; WD40 repeat [structural motif]

cl29593
Location:75 → 465

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001372372.1 → NP_001359301.1 WD repeat-containing protein 17 isoform 4

Status: VALIDATED

Source sequence(s)

AC102933, AC109200

UniProtKB/TrEMBL

E9Q271

Conserved Domains (3) summary

cd00200
Location:391 → 681

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:357 → 391

7WD40; WD40 repeat [structural motif]

cl29593
Location:75 → 465

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001372373.1 → NP_001359302.1 WD repeat-containing protein 17 isoform 5

Status: VALIDATED

Source sequence(s)

AC102933, AC109200

Consensus CDS

CCDS90399.1

UniProtKB/TrEMBL

H3BLI8, Q8CFX0

Related

ENSMUSP00000135805.2, ENSMUST00000175915.8

Conserved Domains (3) summary

cd00200
Location:367 → 657

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:333 → 367

7WD40; WD40 repeat [structural motif]

cl29593
Location:51 → 441

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001372374.1 → NP_001359303.1 WD repeat-containing protein 17 isoform 6

Status: VALIDATED

Source sequence(s)

AC102933, AC109200

UniProtKB/TrEMBL

Q8CFX0

Conserved Domains (3) summary

COG2319
Location:1 → 241

WD40; WD40 repeat [General function prediction only]

cd00200
Location:188 → 478

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:154 → 188

7WD40; WD40 repeat [structural motif]
NM_001372375.1 → NP_001359304.1 WD repeat-containing protein 17 isoform 7

Status: VALIDATED

Source sequence(s)

AC102933, AC109200

UniProtKB/TrEMBL

Q8CFX0

Conserved Domains (3) summary

cd00200
Location:109 → 399

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:75 → 109

7WD40; WD40 repeat [structural motif]

cl29593
Location:2 → 183

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001372376.1 → NP_001359305.1 WD repeat-containing protein 17 isoform 8

Status: VALIDATED

Source sequence(s)

AC102933, AC109200

Conserved Domains (2) summary

cd00200
Location:13 → 303

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:19 → 56

7WD40; WD40 repeat [structural motif]
NM_001428363.1 → NP_001415292.1 WD repeat-containing protein 17 isoform 9

Status: VALIDATED

Source sequence(s)

AC102933, AC109200
NM_028220.4 → NP_082496.3 WD repeat-containing protein 17 isoform 1

See identical proteins and their annotated locations for NP_082496.3

Status: VALIDATED

Source sequence(s)

AC102933, AC109200

Consensus CDS

CCDS22309.2

UniProtKB/TrEMBL

G3UVU7, Q8CFX0

Related

ENSMUSP00000117710.3, ENSMUST00000144711.9

Conserved Domains (4) summary

COG2319
Location:253 → 665

WD40; WD40 repeat [General function prediction only]

cd00200
Location:374 → 664

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:340 → 374

7WD40; WD40 repeat [structural motif]

cl02567
Location:74 → 281

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000074.7 Reference GRCm39 C57BL/6J

Range

55082316..55180014 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036154031.1 → XP_036009924.1 WD repeat-containing protein 17 isoform X12

UniProtKB/TrEMBL

Q8CFX0

Conserved Domains (3) summary

cd00200
Location:109 → 399

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:75 → 109

7WD40; WD40 repeat [structural motif]

cl29593
Location:2 → 183

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006509431.4 → XP_006509494.1 WD repeat-containing protein 17 isoform X5

See identical proteins and their annotated locations for XP_006509494.1

UniProtKB/TrEMBL

Q8CFX0

Conserved Domains (3) summary

cd00200
Location:293 → 583

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:259 → 293

7WD40; WD40 repeat [structural motif]

cl29593
Location:90 → 405

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_036154030.1 → XP_036009923.1 WD repeat-containing protein 17 isoform X11

UniProtKB/TrEMBL

Q8CFX0

Conserved Domains (3) summary

smart00320
Location:49 → 88

WD40; WD40 repeats

cd00200
Location:216 → 445

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:208 → 243

7WD40; WD40 repeat [structural motif]
XM_036154029.1 → XP_036009922.1 WD repeat-containing protein 17 isoform X9

UniProtKB/TrEMBL

Q8CFX0

Conserved Domains (3) summary

COG2319
Location:25 → 295

WD40; WD40 repeat [General function prediction only]

cd00200
Location:242 → 532

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:208 → 242

7WD40; WD40 repeat [structural motif]
XM_030243543.2 → XP_030099403.1 WD repeat-containing protein 17 isoform X6

UniProtKB/TrEMBL

Q8CFX0

Conserved Domains (3) summary

cd00200
Location:293 → 583

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:259 → 293

7WD40; WD40 repeat [structural motif]

cl29593
Location:90 → 405

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006509430.4 → XP_006509493.1 WD repeat-containing protein 17 isoform X5

See identical proteins and their annotated locations for XP_006509493.1

UniProtKB/TrEMBL

Q8CFX0

Conserved Domains (3) summary

cd00200
Location:293 → 583

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:259 → 293

7WD40; WD40 repeat [structural motif]

cl29593
Location:90 → 405

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_036154028.1 → XP_036009921.1 WD repeat-containing protein 17 isoform X8

Conserved Domains (3) summary

COG2319
Location:49 → 319

WD40; WD40 repeat [General function prediction only]

cd00200
Location:266 → 556

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:232 → 266

7WD40; WD40 repeat [structural motif]
XM_006509432.3 → XP_006509495.1 WD repeat-containing protein 17 isoform X7

UniProtKB/TrEMBL

E9Q271

Conserved Domains (3) summary

COG2319
Location:49 → 319

WD40; WD40 repeat [General function prediction only]

cd00200
Location:266 → 556

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:232 → 266

7WD40; WD40 repeat [structural motif]
XM_006509429.4 → XP_006509492.1 WD repeat-containing protein 17 isoform X2

UniProtKB/TrEMBL

E9Q271

Conserved Domains (3) summary

COG2319
Location:44 → 429

WD40; WD40 repeat [General function prediction only]

cd00200
Location:376 → 666

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:342 → 376

7WD40; WD40 repeat [structural motif]
XM_036154025.1 → XP_036009918.1 WD repeat-containing protein 17 isoform X4

UniProtKB/TrEMBL

E9Q271

Conserved Domains (3) summary

cd00200
Location:258 → 594

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:357 → 392

7WD40; WD40 repeat [structural motif]

cl29593
Location:74 → 298

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006509426.4 → XP_006509489.1 WD repeat-containing protein 17 isoform X1

See identical proteins and their annotated locations for XP_006509489.1

UniProtKB/TrEMBL

E9Q271

Related

ENSMUSP00000115550.3, ENSMUST00000127511.9

Conserved Domains (3) summary

cd00200
Location:391 → 681

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:357 → 391

7WD40; WD40 repeat [structural motif]

cl29593
Location:75 → 465

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006509434.4 → XP_006509497.1 WD repeat-containing protein 17 isoform X13

Conserved Domains (2) summary

cd00200
Location:13 → 303

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:19 → 56

7WD40; WD40 repeat [structural motif]
XM_030243544.2 → XP_030099404.1 WD repeat-containing protein 17 isoform X10

UniProtKB/TrEMBL

Q8CFX0

Conserved Domains (3) summary

COG2319
Location:41 → 221

WD40; WD40 repeat [General function prediction only]

cd00200
Location:168 → 458

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:134 → 168

7WD40; WD40 repeat [structural motif]
XM_006509427.5 → XP_006509490.1 WD repeat-containing protein 17 isoform X1

See identical proteins and their annotated locations for XP_006509490.1

UniProtKB/TrEMBL

E9Q271

Conserved Domains (3) summary

cd00200
Location:391 → 681

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:357 → 391

7WD40; WD40 repeat [structural motif]

cl29593
Location:75 → 465

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_030243540.2 → XP_030099400.1 WD repeat-containing protein 17 isoform X3

UniProtKB/TrEMBL

Q8C8Y2, Q8CFX0

Conserved Domains (3) summary

cd00200
Location:367 → 657

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:333 → 367

7WD40; WD40 repeat [structural motif]

cl29593
Location:51 → 441

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...