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    Cox7b2 cytochrome c oxidase subunit 7B2 [ Mus musculus (house mouse) ]

    Gene ID: 78174, updated on 27-Nov-2024

    Summary

    Official Symbol
    Cox7b2provided by MGI
    Official Full Name
    cytochrome c oxidase subunit 7B2provided by MGI
    Primary source
    MGI:MGI:1925424
    See related
    Ensembl:ENSMUSG00000049387 AllianceGenome:MGI:1925424
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930503B16Rik
    Summary
    Acts upstream of or within spermatogenesis. Predicted to be located in membrane. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrion. Is expressed in several structures, including gonad; liver; lung; muscle tissue; and spleen. Orthologous to human COX7B2 (cytochrome c oxidase subunit 7B2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 53.3) See more
    Orthologs
    NEW
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    Genomic context

    See Cox7b2 in Genome Data Viewer
    Location:
    5 C3.2; 5 37.98 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (71600166..71705548, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (71442823..71548205, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene gamma-aminobutyric acid type A receptor subunit gamma 1 Neighboring gene STARR-seq mESC enhancer starr_13345 Neighboring gene STARR-seq mESC enhancer starr_13346 Neighboring gene gamma-aminobutyric acid type A receptor subunit alpha 2 Neighboring gene STARR-seq mESC enhancer starr_13347 Neighboring gene STARR-seq mESC enhancer starr_13349 Neighboring gene STARR-seq mESC enhancer starr_13350 Neighboring gene STARR-seq mESC enhancer starr_13351 Neighboring gene STARR-seq mESC enhancer starr_13352 Neighboring gene STARR-seq mESC enhancer starr_13353 Neighboring gene STARR-seq mESC enhancer starr_13354 Neighboring gene gamma-aminobutyric acid type A receptor subunit alpha 4 Neighboring gene gamma-aminobutyric acid type A receptor subunit beta 1 Neighboring gene predicted gene, 38562

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, cytochrome c to oxygen IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within sperm motility IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of respiratory chain complex IV IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cytochrome c oxidase subunit VIIb2
    NP_084328.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030052.3NP_084328.1  cytochrome c oxidase subunit VIIb2

      See identical proteins and their annotated locations for NP_084328.1

      Status: VALIDATED

      Source sequence(s)
      BC059709, BY099104
      Consensus CDS
      CCDS39106.1
      UniProtKB/TrEMBL
      Q9D2H1
      Related
      ENSMUSP00000060890.6, ENSMUST00000050129.6
      Conserved Domains (1) summary
      pfam05392
      Location:281
      COX7B; Cytochrome C oxidase chain VIIB

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      71600166..71705548 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)