Allc allantoicase [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Allcprovided by MGI
Official Full Name: allantoicaseprovided by MGI
Primary source: MGI:MGI:2136971
See related: Ensembl:ENSMUSG00000020636 AllianceGenome:MGI:2136971
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Alc; 1700012B22Rik
Summary: Predicted to enable allantoicase activity. Predicted to be involved in allantoin catabolic process. Orthologous to human ALLC (allantoicase). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward testis adult (RPKM 114.4) See more
Orthologs: human all
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Genomic context

Location:: 12 A2; 12 10.97 cM

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (28603754..28632527, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (28553755..28582528, complement)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The loss of allantoicase activity in mouse is due to a low substrate affinity and to a reduced expression level of the enzyme.
Title: Property comparison of recombinant amphibian and mammalian allantoicases.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3) 1 citation
Targeted (1)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:489261

Allc (e-PCR), detects polymorphism
- UniSTS:239184

Allc (e-PCR), detects polymorphism
- UniSTS:546649

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables allantoicase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in allantoin catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: probable inactive allantoicase

Names: allantoate amidinohydrolase; probable allantoicase

NP_001351288.1

EC 3.5.3.4

NP_444386.2

EC 3.5.3.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.