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    LINC02145 long intergenic non-protein coding RNA 2145 [ Homo sapiens (human) ]

    Gene ID: 401172, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC02145provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 2145provided by HGNC
    Primary source
    HGNC:HGNC:53005
    See related
    Ensembl:ENSG00000250490 AllianceGenome:HGNC:53005
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC02145 in Genome Data Viewer
    Location:
    5p15.31
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (6310441..6337292, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (6239112..6266063, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (6310554..6337405, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374636 Neighboring gene Sharpr-MPRA regulatory region 9370 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15895 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr5:5943193-5944392 Neighboring gene NANOG hESC enhancer GRCh37_chr5:6038201-6038702 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr5:6158863-6160062 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22328 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:6315844-6316069 Neighboring gene high mobility group box 3 pseudogene 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:6343159-6343659 Neighboring gene Sharpr-MPRA regulatory region 13881 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:6367530-6367697 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22329 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22330 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr5:6408294-6409493 Neighboring gene uncharacterized LOC124900933 Neighboring gene mediator complex subunit 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Long non-coding RNA FLJ33360 participates in ovarian cancer progression by sponging miR-30b-3p. Yang M, et al. Onco Targets Ther, 2019. PMID 31239715, Free PMC Article
    2. Ischemic stroke is associated with the ABO locus: the EuroCLOT study. Williams FM, et al. Ann Neurol, 2013 Jan. PMID 23381943, Free PMC Article
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614, Free PMC Article
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Other Names

    • CTD-2324F15.2

    Clone Names

    • FLJ33360

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_028351.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010635, AK090679
      Related
      ENST00000507444.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      6310441..6337292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791776.1 Reference GRCh38.p14 PATCHES

      Range
      12615..39466 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      6239112..6266063 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001001702.1: Suppressed sequence

      Description
      NM_001001702.1: This RefSeq was permanently suppressed because currently there is insufficient support for the protein, and a significant portion of the transcript is repetitive sequence.
    Nucleotide Protein
    Heading Accession and Version

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