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    Itfg1 integrin alpha FG-GAP repeat containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 71927, updated on 9-Dec-2024

    Summary

    Official Symbol
    Itfg1provided by MGI
    Official Full Name
    integrin alpha FG-GAP repeat containing 1provided by MGI
    Primary source
    MGI:MGI:106419
    See related
    Ensembl:ENSMUSG00000031703 AllianceGenome:MGI:106419
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cda08; D8Wsu49e; 2310047C21Rik
    Summary
    Predicted to be located in extracellular region and membrane. Predicted to be active in plasma membrane. Is expressed in extraembryonic component; nervous system; and neural retina. Orthologous to human ITFG1 (integrin alpha FG-GAP repeat containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 25.3), frontal lobe adult (RPKM 22.2) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Itfg1 in Genome Data Viewer
    Location:
    8 C3; 8 41.61 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (86444186..86567578, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (85717557..85840949, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53447 Neighboring gene neuropilin (NRP) and tolloid (TLL)-like 2 Neighboring gene microRNA 8109 Neighboring gene predicted gene, 39214 Neighboring gene STARR-seq mESC enhancer starr_22171 Neighboring gene ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit E, pseudogene 1 Neighboring gene potassium channel tetramerisation domain containing 7 pseudogene Neighboring gene phosphorylase kinase beta Neighboring gene STARR-seq mESC enhancer starr_22173 Neighboring gene STARR-seq mESC enhancer starr_22174 Neighboring gene kallikrein related-peptidase 7 (chymotryptic, stratum corneum) pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    T-cell immunomodulatory protein
    Names
    integrin-alpha FG-GAP repeat-containing protein 1
    linkin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028007.3NP_082283.2  T-cell immunomodulatory protein precursor

      See identical proteins and their annotated locations for NP_082283.2

      Status: VALIDATED

      Source sequence(s)
      AK132242, AK141948, AV257002, BP765330, DN175510
      Consensus CDS
      CCDS40424.1
      UniProtKB/Swiss-Prot
      E9QQ11, Q99KW9, Q9D6X1
      Related
      ENSMUSP00000034140.8, ENSMUST00000034140.9
      Conserved Domains (1) summary
      pfam13517
      Location:54117
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      86444186..86567578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)