Pbsn probasin [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Pbsnprovided by MGI
Official Full Name: probasinprovided by MGI
Primary source: MGI:MGI:1860484
See related: Ensembl:ENSMUSG00000000003 AllianceGenome:MGI:1860484
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: PB; Prbs
Summary: Predicted to enable odorant binding activity. Located in extracellular region. Is expressed in anterior prostate gland; prostate gland dorsolateral lobe; and ventral prostate gland. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: X B; X 38.32 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (76881504..76897132, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (77837898..77853500, complement)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Androgen receptor DNA binding domain is able to bind to its cognate sequences within the probasin promoter in a way that is indifferent to the presence or absence of histones and nucleosomal structure.
Title: Probasin promoter assembles into a strongly positioned nucleosome that permits androgen receptor binding.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (4)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:493086

Pbsn (e-PCR), detects polymorphism
- UniSTS:463463

NoName (e-PCR)
- UniSTS:493942

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables odorant binding	IBA Inferred from Biological aspect of Ancestor more info
enables small molecule binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IDA Inferred from Direct Assay more info	PubMed
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: probasin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.