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    Ubxn10 UBX domain protein 10 [ Mus musculus (house mouse) ]

    Gene ID: 212190, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ubxn10provided by MGI
    Official Full Name
    UBX domain protein 10provided by MGI
    Primary source
    MGI:MGI:2443123
    See related
    Ensembl:ENSMUSG00000043621 AllianceGenome:MGI:2443123
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ubxd3; A830047D02; 5730509E04Rik
    Summary
    Predicted to enable ubiquitin binding activity. Predicted to be involved in ERAD pathway and cilium assembly. Predicted to be located in cilium. Predicted to be part of intraciliary transport particle B. Predicted to be active in endoplasmic reticulum. Is expressed in sensory organ and skeleton. Orthologous to human UBXN10 (UBX domain protein 10). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 108.6), ovary adult (RPKM 10.0) and 1 other tissue See more
    Orthologs
    human all
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    Genomic context

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    See Ubxn10 in Genome Data Viewer
    Location:
    4 D3; 4 70.53 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (138437148..138465749, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (138709837..138738438, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_11810 Neighboring gene von Willebrand factor A domain containing 5B1 Neighboring gene predicted gene, 32662 Neighboring gene predicted gene, 32770 Neighboring gene STARR-seq mESC enhancer starr_11814 Neighboring gene phospholipase A2, group IIC Neighboring gene predicted gene, 57720 Neighboring gene phospholipase A2, group IIF Neighboring gene predicted gene, 42332

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
    2. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cilium ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cilium ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of intraciliary transport particle B ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of intraciliary transport particle B ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    UBX domain-containing protein 10
    Names
    UBX domain containing 3
    UBX domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001285928.1 → NP_001272857.1  UBX domain-containing protein 10

      See identical proteins and their annotated locations for NP_001272857.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3 and 4 all encode the same protein.
      Source sequence(s)
      AK046949, AK161245
      Consensus CDS
      CCDS18830.1
      UniProtKB/Swiss-Prot
      Q3TTR1, Q8BG34, Q8BP58, Q8R0B6
      UniProtKB/TrEMBL
      Q3TTM2
      Related
      ENSMUSP00000101436.2, ENSMUST00000105810.8
      Conserved Domains (1) summary
      cl00155
      Location:190 → 266
      UBQ; Ubiquitin-like proteins

    2. NM_001285929.1 → NP_001272858.1  UBX domain-containing protein 10

      See identical proteins and their annotated locations for NP_001272858.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
      Source sequence(s)
      AK161245, AL844178
      Consensus CDS
      CCDS18830.1
      UniProtKB/Swiss-Prot
      Q3TTR1, Q8BG34, Q8BP58, Q8R0B6
      UniProtKB/TrEMBL
      Q3TTM2
      Conserved Domains (1) summary
      cl00155
      Location:190 → 266
      UBQ; Ubiquitin-like proteins

    3. NM_001285930.1 → NP_001272859.1  UBX domain-containing protein 10

      See identical proteins and their annotated locations for NP_001272859.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
      Source sequence(s)
      AK161245, AL844178
      Consensus CDS
      CCDS18830.1
      UniProtKB/Swiss-Prot
      Q3TTR1, Q8BG34, Q8BP58, Q8R0B6
      UniProtKB/TrEMBL
      Q3TTM2
      Related
      ENSMUSP00000101435.2, ENSMUST00000105809.2
      Conserved Domains (1) summary
      cl00155
      Location:190 → 266
      UBQ; Ubiquitin-like proteins

    4. NM_178671.5 → NP_848786.1  UBX domain-containing protein 10

      See identical proteins and their annotated locations for NP_848786.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
      Source sequence(s)
      AK077656, AK161245
      Consensus CDS
      CCDS18830.1
      UniProtKB/Swiss-Prot
      Q3TTR1, Q8BG34, Q8BP58, Q8R0B6
      UniProtKB/TrEMBL
      Q3TTM2
      Related
      ENSMUSP00000101437.3, ENSMUST00000105811.9
      Conserved Domains (1) summary
      cl00155
      Location:190 → 266
      UBQ; Ubiquitin-like proteins

    RNA

    1. NR_104373.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) contains alternate 3' exon structure compared to variant 1. This variant is represented as non-coding because use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK045964, AK077656, AW494942

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      138437148..138465749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BG34.1 GenPept UniProtKB/Swiss-Prot:Q8BG34

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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