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    Prr14l proline rich 14-like [ Mus musculus (house mouse) ]

    Gene ID: 215476, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Prr14lprovided by MGI
    Official Full Name
    proline rich 14-likeprovided by MGI
    Primary source
    MGI:MGI:2443658
    See related
    Ensembl:ENSMUSG00000054280 AllianceGenome:MGI:2443658
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Prl14l; 6030436E02Rik; C330019G07Rik
    Summary
    Is expressed in medial ganglionic eminence. Orthologous to human PRR14L (proline rich 14 like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in thymus adult (RPKM 5.3), ovary adult (RPKM 4.2) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Prr14l in Genome Data Viewer
    Location:
    5 B1; 5 17.33 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (32946551..33011679, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (32789207..32854337, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene 2420 Neighboring gene predicted gene, 52771 Neighboring gene STARR-seq mESC enhancer starr_12804 Neighboring gene phosphatidylserine decarboxylase Neighboring gene STARR-positive B cell enhancer ABC_E4751 Neighboring gene ribosomal protein L37 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10312 Neighboring gene DEP domain containing 5 Neighboring gene predicted gene, 24003 Neighboring gene STARR-seq mESC enhancer starr_12808 Neighboring gene STARR-seq mESC enhancer starr_12809 Neighboring gene STARR-seq mESC enhancer starr_12810 Neighboring gene predicted gene, 57845 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Expression of the novel gene embryo implantation factor 2 (EMO2) in the mouse uterus at the implantation sites. Sun Z, et al. Fertil Steril, 2009 May. PMID 18384781
    2. The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain. Cajigas I, et al. Mol Cell, 2018 Sep 20. PMID 30146317, Free PMC Article
    3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    5. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein PRR14L

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_194340.2 → NP_919321.2  protein PRR14L

      Status: VALIDATED

      Source sequence(s)
      AC108773, AC241622, AK134346, BC094374
      Consensus CDS
      CCDS19195.2
      UniProtKB/TrEMBL
      E9Q7C4
      Related
      ENSMUSP00000113259.3, ENSMUST00000120129.9
      Conserved Domains (1) summary
      pfam15386
      Location:1842 → 1895
      Tantalus; Drosophila Tantalus-like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      32946551..33011679 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503842.5 → XP_006503905.1  protein PRR14L isoform X8

      Conserved Domains (1) summary
      pfam15386
      Location:1714 → 1767
      Tantalus; Drosophila Tantalus-like

    2. XM_017320798.3 → XP_017176287.1  protein PRR14L isoform X7

      Conserved Domains (1) summary
      pfam15386
      Location:1757 → 1810
      Tantalus; Drosophila Tantalus-like

    3. XM_006503836.5 → XP_006503899.1  protein PRR14L isoform X2

      UniProtKB/TrEMBL
      E9Q7C4
      Conserved Domains (1) summary
      pfam15386
      Location:1842 → 1895
      Tantalus; Drosophila Tantalus-like

    4. XM_017320791.3 → XP_017176280.1  protein PRR14L isoform X1

      Conserved Domains (1) summary
      pfam15386
      Location:1885 → 1938
      Tantalus; Drosophila Tantalus-like

    5. XM_017320792.3 → XP_017176281.1  protein PRR14L isoform X1

      Conserved Domains (1) summary
      pfam15386
      Location:1885 → 1938
      Tantalus; Drosophila Tantalus-like

    6. XM_036164991.1 → XP_036020884.1  protein PRR14L isoform X1

      Conserved Domains (1) summary
      pfam15386
      Location:1885 → 1938
      Tantalus; Drosophila Tantalus-like

    7. XM_006503843.5 → XP_006503906.1  protein PRR14L isoform X9

      Conserved Domains (1) summary
      pfam15386
      Location:1695 → 1748
      Tantalus; Drosophila Tantalus-like

    8. XM_030254361.2 → XP_030110221.1  protein PRR14L isoform X10

      Conserved Domains (1) summary
      pfam15386
      Location:1636 → 1689
      Tantalus; Drosophila Tantalus-like

    9. XM_030254360.1 → XP_030110220.1  protein PRR14L isoform X2

      UniProtKB/TrEMBL
      E9Q7C4
      Conserved Domains (1) summary
      pfam15386
      Location:1842 → 1895
      Tantalus; Drosophila Tantalus-like

    10. XM_017320793.1 → XP_017176282.1  protein PRR14L isoform X1

      Conserved Domains (1) summary
      pfam15386
      Location:1885 → 1938
      Tantalus; Drosophila Tantalus-like

    11. XM_017320794.3 → XP_017176283.1  protein PRR14L isoform X3

    12. XM_017320797.3 → XP_017176286.1  protein PRR14L isoform X5

    13. XM_017320795.3 → XP_017176284.1  protein PRR14L isoform X4

    14. XM_017320796.3 → XP_017176285.1  protein PRR14L isoform X6

    Nucleotide Protein Strain
    Heading Accession and Version

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