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    Rpl36 ribosomal protein L36 [ Mus musculus (house mouse) ]

    Gene ID: 54217, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Rpl36provided by MGI
    Official Full Name
    ribosomal protein L36provided by MGI
    Primary source
    MGI:MGI:1860603
    See related
    Ensembl:ENSMUSG00000057863 AllianceGenome:MGI:1860603
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in brain. Orthologous to human RPL36 (ribosomal protein L36). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 495.6), colon adult (RPKM 440.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rpl36 in Genome Data Viewer
    Location:
    17 D; 17 29.42 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (56917094..56921246)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (56610094..56614246)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene scaffold attachment factor B Neighboring gene STARR-positive B cell enhancer ABC_E8687 Neighboring gene mitochondrial contact site and cristae organizing system subunit 13 Neighboring gene lon peptidase 1, mitochondrial Neighboring gene STARR-positive B cell enhancer ABC_E3210 Neighboring gene cation channel sperm associated auxiliary subunit delta Neighboring gene predicted gene, 33461

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression. Nakagawa T, et al. iScience, 2020 Apr 24. PMID 32299058, Free PMC Article
    2. Uncovering a mammalian neural-specific poly(A) binding protein with unique properties. Sharma S, et al. Genes Dev, 2023 Aug 1. PMID 37704377, Free PMC Article
    3. Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. Chen J, et al. Genes Dev, 2011 Apr 1. PMID 21460039, Free PMC Article
    4. The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Basta JM, et al. Dev Biol, 2020 Aug 15. PMID 32504627, Free PMC Article
    5. A male germ-cell-specific ribosome controls male fertility. Li H, et al. Nature, 2022 Dec. PMID 36517592

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in translation at postsynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in translation at presynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in presynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    large ribosomal subunit protein eL36
    Names
    60S ribosomal protein L36

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018730.3 → NP_061200.2  large ribosomal subunit protein eL36

      See identical proteins and their annotated locations for NP_061200.2

      Status: VALIDATED

      Source sequence(s)
      AK003115, BY055319, CF728650
      Consensus CDS
      CCDS37665.1
      UniProtKB/Swiss-Prot
      P47964, Q6ZWZ4
      UniProtKB/TrEMBL
      Q5M9L1
      Related
      ENSMUSP00000079340.6, ENSMUST00000080492.7
      Conserved Domains (1) summary
      pfam01158
      Location:4 → 94
      Ribosomal_L36e; Ribosomal protein L36e

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      56917094..56921246
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249907.1 → XP_030105767.1  large ribosomal subunit protein eL36 isoform X1

      UniProtKB/Swiss-Prot
      P47964, Q6ZWZ4
      UniProtKB/TrEMBL
      Q5M9L1
      Conserved Domains (1) summary
      pfam01158
      Location:4 → 94
      Ribosomal_L36e; Ribosomal protein L36e
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47964.3 GenPept UniProtKB/Swiss-Prot:P47964

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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