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    Tex261 testis expressed 261 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297392, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tex261provided by RGD
    Official Full Name
    testis expressed 261provided by RGD
    Primary source
    RGD:1305851
    See related
    EnsemblRapid:ENSRNOG00000013712 AllianceGenome:RGD:1305851
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable COPII receptor activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to act upstream of or within positive regulation of apoptotic process. Predicted to be located in cytoplasm and membrane. Predicted to be active in COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum membrane. Orthologous to human TEX261 (testis expressed 261). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 155.1), Heart (RPKM 149.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tex261 in Genome Data Viewer
    Location:
    4q34
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (117813050..117818408, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (116253547..116260730, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (115446830..115454035, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene ATPase H+ transporting V1 subunit B1 Neighboring gene ankyrin repeat domain 53 Neighboring gene uncharacterized LOC134486595 Neighboring gene 60S ribosomal protein L27 pseudogene Neighboring gene N-acetylglucosamine kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Tex261 modulates the excitotoxic cell death induced by N-methyl-D-aspartate (NMDA) receptor activation. Taniura H, et al. Biochem Biophys Res Commun, 2007 Nov 3. PMID 17803966
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC109238

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables COPII receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables COPII receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein TEX261
    Names
    testis expressed gene 261

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017537.1 → NP_001017537.1  protein TEX261

      See identical proteins and their annotated locations for NP_001017537.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091302
      UniProtKB/Swiss-Prot
      Q5BJW3
      UniProtKB/TrEMBL
      A0A8L2QVX6, A6IAP6
      Related
      ENSRNOP00000106719.1, ENSRNOT00000150448.1
      Conserved Domains (1) summary
      pfam04148
      Location:1 → 186
      Erv26; Transmembrane adaptor Erv26

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      117813050..117818408 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017592548.3 → XP_017448037.1  protein TEX261 isoform X2

      Conserved Domains (1) summary
      pfam04148
      Location:1 → 147
      Erv26; Transmembrane adaptor Erv26

    2. XM_008763059.4 → XP_008761281.1  protein TEX261 isoform X1

      UniProtKB/TrEMBL
      A0A8L2QVX6
      Conserved Domains (1) summary
      pfam04148
      Location:1 → 194
      Erv26; Transmembrane adaptor Erv26

    3. XM_039107343.2 → XP_038963271.1  protein TEX261 isoform X2

      Conserved Domains (1) summary
      pfam04148
      Location:1 → 147
      Erv26; Transmembrane adaptor Erv26

    4. XM_008763061.4 → XP_008761283.1  protein TEX261 isoform X2

      See identical proteins and their annotated locations for XP_008761283.1

      Conserved Domains (1) summary
      pfam04148
      Location:1 → 147
      Erv26; Transmembrane adaptor Erv26
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BJW3.1 GenPept UniProtKB/Swiss-Prot:Q5BJW3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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