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    Zfp638 zinc finger protein 638 [ Mus musculus (house mouse) ]

    Gene ID: 18139, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp638provided by MGI
    Official Full Name
    zinc finger protein 638provided by MGI
    Primary source
    MGI:MGI:1203484
    See related
    Ensembl:ENSMUSG00000030016 AllianceGenome:MGI:1203484
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfml; Np220; Znf638; mNP220
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and sensory organ. Orthologous to human ZNF638 (zinc finger protein 638). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 14.4), CNS E14 (RPKM 10.9) and 20 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp638 in Genome Data Viewer
    Location:
    6 C3; 6 36.06 cM
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (83844050..83963855)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (83867068..83986871)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L18 pseudogene Neighboring gene ribosomal protein S8 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E8111 Neighboring gene STARR-seq mESC enhancer starr_16471 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 33024 Neighboring gene dysferlin Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A family of novel DNA-binding nuclear proteins having polypyrimidine tract-binding motif and arginine/serine-rich motif. Matsushima Y, et al. Biochem Biophys Res Commun, 1996 Jun 14. PMID 8670298
    2. The adipogenic transcriptional cofactor ZNF638 interacts with splicing regulators and influences alternative splicing. Du C, et al. J Lipid Res, 2014 Sep. PMID 25024404, Free PMC Article
    3. Regulation of adipocyte differentiation by the zinc finger protein ZNF638. Meruvu S, et al. J Biol Chem, 2011 Jul 29. PMID 21602272, Free PMC Article
    4. Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner. Meng M, et al. Metabolism, 2024 Mar. PMID 38211696
    5. USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638. Ni W, et al. Cell Death Dis, 2020 Oct 10. PMID 33040080, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner.
      Title: Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner.
    2. USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638.
      Title: USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638.
    3. ZNF638 participates in splicing decisions and that it may control adipogenesis through regulation of the relative amounts of differentiation-specific isoforms.
      Title: The adipogenic transcriptional cofactor ZNF638 interacts with splicing regulators and influences alternative splicing.
    4. ZNF638 is a novel and early regulator of adipogenesis that works as a transcription cofactor of C/EBPs.
      Title: Regulation of adipocyte differentiation by the zinc finger protein ZNF638.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 638
    Names
    nuclear protein 220
    zinc finger matrin-like protein
    zinc finger, matrin-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166371.2 → NP_001159843.1  zinc finger protein 638 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283
      Consensus CDS
      CCDS51823.1
      UniProtKB/TrEMBL
      A0A0N4SVI8
      Related
      ENSMUSP00000109466.4, ENSMUST00000113835.10
      Conserved Domains (4) summary
      smart00451
      Location:1220 → 1252
      ZnF_U1; U1-like zinc finger
      cd12436
      Location:983 → 1056
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:879 → 953
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:676 → 751
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. NM_001355284.2 → NP_001342213.1  zinc finger protein 638 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283
      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      Conserved Domains (6) summary
      smart00451
      Location:1858 → 1890
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:1043 → 1386
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd12436
      Location:955 → 1028
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:851 → 925
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      TIGR01649
      Location:852 → 1152
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cl17169
      Location:676 → 751
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. NM_001355285.2 → NP_001342214.1  zinc finger protein 638 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283
      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      Conserved Domains (7) summary
      smart00451
      Location:1824 → 1856
      ZnF_U1; U1-like zinc finger
      cd12436
      Location:955 → 1028
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:851 → 925
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      TIGR01649
      Location:852 → 1152
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      pfam05110
      Location:549 → 674
      AF-4; AF-4 proto-oncoprotein
      cl17169
      Location:676 → 751
      RRM_SF; RNA recognition motif (RRM) superfamily
      cl26950
      Location:1043 → 1386
      LsmAD; LsmAD domain

    4. NM_001355286.2 → NP_001342215.1  zinc finger protein 638 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283
      Consensus CDS
      CCDS20288.1
      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      UniProtKB/TrEMBL
      A0A0N4SV80
      Conserved Domains (8) summary
      smart00451
      Location:1875 → 1907
      ZnF_U1; U1-like zinc finger
      cd12436
      Location:1006 → 1079
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:902 → 976
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      TIGR01649
      Location:903 → 1203
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      pfam05110
      Location:549 → 674
      AF-4; AF-4 proto-oncoprotein
      cl17169
      Location:676 → 751
      RRM_SF; RNA recognition motif (RRM) superfamily
      cl26511
      Location:740 → 900
      Neuromodulin_N; Gap junction protein N-terminal region
      cl26950
      Location:1094 → 1437
      LsmAD; LsmAD domain

    5. NM_001406071.1 → NP_001393000.1  zinc finger protein 638 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    6. NM_001406072.1 → NP_001393001.1  zinc finger protein 638 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    7. NM_001406073.1 → NP_001393002.1  zinc finger protein 638 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    8. NM_001406074.1 → NP_001393003.1  zinc finger protein 638 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283
      UniProtKB/TrEMBL
      E9QML5
      Related
      ENSMUSP00000032088.9, ENSMUST00000032088.14

    9. NM_001406075.1 → NP_001393004.1  zinc finger protein 638 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    10. NM_001406076.1 → NP_001393005.1  zinc finger protein 638 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    11. NM_001406077.1 → NP_001393006.1  zinc finger protein 638 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    12. NM_001406078.1 → NP_001393007.1  zinc finger protein 638 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283
      UniProtKB/TrEMBL
      A0A0N4SV38
      Related
      ENSMUSP00000144939.2, ENSMUST00000203891.3

    13. NM_001406079.1 → NP_001393008.1  zinc finger protein 638 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    14. NM_001406080.1 → NP_001393009.1  zinc finger protein 638 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    15. NM_001406081.1 → NP_001393010.1  zinc finger protein 638 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    16. NM_001406082.1 → NP_001393011.1  zinc finger protein 638 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    17. NM_001406083.1 → NP_001393012.1  zinc finger protein 638 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    18. NM_001406084.1 → NP_001393013.1  zinc finger protein 638 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    19. NM_008717.4 → NP_032743.2  zinc finger protein 638 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283
      Consensus CDS
      CCDS20288.1
      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      UniProtKB/TrEMBL
      A0A0N4SV80
      Related
      ENSMUSP00000144989.2, ENSMUST00000204751.3
      Conserved Domains (8) summary
      smart00451
      Location:1875 → 1907
      ZnF_U1; U1-like zinc finger
      cd12436
      Location:1006 → 1079
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:902 → 976
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      TIGR01649
      Location:903 → 1203
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      pfam05110
      Location:549 → 674
      AF-4; AF-4 proto-oncoprotein
      cl17169
      Location:676 → 751
      RRM_SF; RNA recognition motif (RRM) superfamily
      cl26511
      Location:740 → 900
      Neuromodulin_N; Gap junction protein N-terminal region
      cl26950
      Location:1094 → 1437
      LsmAD; LsmAD domain

    RNA

    1. NR_176013.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC153607, AC156283

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      83844050..83963855
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505704.4 → XP_006505767.1  zinc finger protein 638 isoform X1

      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      Conserved Domains (7) summary
      PTZ00121
      Location:836 → 996
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:2005 → 2037
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:1190 → 1533
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd12436
      Location:1102 → 1175
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:998 → 1072
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      TIGR01649
      Location:999 → 1299
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. XM_006505711.5 → XP_006505774.1  zinc finger protein 638 isoform X11

      UniProtKB/TrEMBL
      A0A0N4SVI8
      Related
      ENSMUSP00000145124.2, ENSMUST00000203324.3
      Conserved Domains (5) summary
      PTZ00121
      Location:836 → 996
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:1318 → 1350
      ZnF_U1; U1-like zinc finger
      cd12436
      Location:1102 → 1175
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:998 → 1072
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_006505712.5 → XP_006505775.1  zinc finger protein 638 isoform X13

      UniProtKB/TrEMBL
      A0A0N4SVI8
      Conserved Domains (5) summary
      PTZ00121
      Location:836 → 996
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:1284 → 1316
      ZnF_U1; U1-like zinc finger
      cd12436
      Location:1102 → 1175
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:998 → 1072
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    4. XM_006505705.5 → XP_006505768.1  zinc finger protein 638 isoform X2

      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      Conserved Domains (7) summary
      PTZ00121
      Location:836 → 973
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:1982 → 2014
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:1167 → 1510
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd12436
      Location:1079 → 1152
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:975 → 1049
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      TIGR01649
      Location:976 → 1276
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    5. XM_017321429.3 → XP_017176918.1  zinc finger protein 638 isoform X5

      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      Conserved Domains (6) summary
      PTZ00121
      Location:836 → 973
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:1948 → 1980
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:1167 → 1510
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd12436
      Location:1079 → 1152
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:975 → 1049
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    6. XM_017321435.3 → XP_017176924.1  zinc finger protein 638 isoform X12

      UniProtKB/TrEMBL
      A0A0N4SVI8
      Conserved Domains (5) summary
      PTZ00121
      Location:836 → 973
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:1295 → 1327
      ZnF_U1; U1-like zinc finger
      cd12436
      Location:1079 → 1152
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:975 → 1049
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    7. XM_036165916.1 → XP_036021809.1  zinc finger protein 638 isoform X15

      UniProtKB/TrEMBL
      A0A0N4SVI8
      Conserved Domains (4) summary
      PTZ00121
      Location:836 → 973
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:1261 → 1293
      ZnF_U1; U1-like zinc finger
      cd12716
      Location:975 → 1049
      RRM1_2_NP220; RNA recognition motif 1 (RRM1) and 2 (RRM2) found in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    8. XM_036165914.1 → XP_036021807.1  zinc finger protein 638 isoform X14

      UniProtKB/TrEMBL
      A0A0N4SVI8
      Conserved Domains (4) summary
      PRK14907
      Location:847 → 968
      rplD; 50S ribosomal protein L4; Provisional
      smart00451
      Location:1267 → 1299
      ZnF_U1; U1-like zinc finger
      cd12716
      Location:947 → 1021
      RRM1_2_NP220; RNA recognition motif 1 (RRM1) and 2 (RRM2) found in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    9. XM_036165917.1 → XP_036021810.1  zinc finger protein 638 isoform X16

      UniProtKB/TrEMBL
      A0A0N4SVI8
      Conserved Domains (4) summary
      PRK14907
      Location:847 → 968
      rplD; 50S ribosomal protein L4; Provisional
      smart00451
      Location:1233 → 1265
      ZnF_U1; U1-like zinc finger
      cd12716
      Location:947 → 1021
      RRM1_2_NP220; RNA recognition motif 1 (RRM1) and 2 (RRM2) found in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    10. XM_011241247.4 → XP_011239549.1  zinc finger protein 638 isoform X6

      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      Conserved Domains (5) summary
      smart00451
      Location:1931 → 1963
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:1116 → 1459
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd12436
      Location:1028 → 1101
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:924 → 998
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    11. XM_017321437.3 → XP_017176926.1  zinc finger protein 638 isoform X19

      UniProtKB/TrEMBL
      A0A0N4SVI8
      Conserved Domains (4) summary
      PTZ00121
      Location:836 → 996
      PTZ00121; MAEBL; Provisional
      cd12436
      Location:1102 → 1175
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:998 → 1072
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:772 → 847
      RRM_SF; RNA recognition motif (RRM) superfamily

    12. XM_017321434.3 → XP_017176923.1  zinc finger protein 638 isoform X8

      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      UniProtKB/TrEMBL
      E9QML5
      Conserved Domains (7) summary
      PTZ00121
      Location:740 → 900
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:1909 → 1941
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:1094 → 1437
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd12436
      Location:1006 → 1079
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:902 → 976
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      TIGR01649
      Location:903 → 1203
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cl17169
      Location:676 → 751
      RRM_SF; RNA recognition motif (RRM) superfamily

    13. XM_006505709.5 → XP_006505772.1  zinc finger protein 638 isoform X8

      See identical proteins and their annotated locations for XP_006505772.1

      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      UniProtKB/TrEMBL
      E9QML5
      Conserved Domains (7) summary
      PTZ00121
      Location:740 → 900
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:1909 → 1941
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:1094 → 1437
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd12436
      Location:1006 → 1079
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:902 → 976
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      TIGR01649
      Location:903 → 1203
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cl17169
      Location:676 → 751
      RRM_SF; RNA recognition motif (RRM) superfamily

    14. XM_036165913.1 → XP_036021806.1  zinc finger protein 638 isoform X9

      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      Conserved Domains (6) summary
      PTZ00121
      Location:740 → 877
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:1886 → 1918
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:1071 → 1414
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      TIGR01649
      Location:880 → 1180
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cd12716
      Location:879 → 953
      RRM1_2_NP220; RNA recognition motif 1 (RRM1) and 2 (RRM2) found in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:676 → 751
      RRM_SF; RNA recognition motif (RRM) superfamily

    15. XM_030255215.2 → XP_030111075.1  zinc finger protein 638 isoform X9

      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      Conserved Domains (6) summary
      PTZ00121
      Location:740 → 877
      PTZ00121; MAEBL; Provisional
      smart00451
      Location:1886 → 1918
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:1071 → 1414
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      TIGR01649
      Location:880 → 1180
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cd12716
      Location:879 → 953
      RRM1_2_NP220; RNA recognition motif 1 (RRM1) and 2 (RRM2) found in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:676 → 751
      RRM_SF; RNA recognition motif (RRM) superfamily

    16. XM_006505714.5 → XP_006505777.1  zinc finger protein 638 isoform X17

      Conserved Domains (6) summary
      PRK13808
      Location:32 → 160
      PRK13808; adenylate kinase; Provisional
      smart00451
      Location:1191 → 1223
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:376 → 719
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd12436
      Location:288 → 361
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      TIGR01649
      Location:185 → 485
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cl17169
      Location:184 → 258
      RRM_SF; RNA recognition motif (RRM) superfamily

    17. XM_036165919.1 → XP_036021812.1  zinc finger protein 638 isoform X22

      Conserved Domains (5) summary
      smart00451
      Location:1117 → 1149
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:302 → 645
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      TIGR01649
      Location:111 → 411
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cd12716
      Location:110 → 184
      RRM1_2_NP220; RNA recognition motif 1 (RRM1) and 2 (RRM2) found in vertebrate nuclear protein 220 (NP220)
      cl17169
      Location:214 → 272
      RRM_SF; RNA recognition motif (RRM) superfamily

    18. XM_030255216.2 → XP_030111076.1  zinc finger protein 638 isoform X20

      Conserved Domains (5) summary
      smart00451
      Location:1140 → 1172
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:325 → 668
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd12436
      Location:237 → 310
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      TIGR01649
      Location:134 → 434
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cl17169
      Location:133 → 207
      RRM_SF; RNA recognition motif (RRM) superfamily

    19. XM_006505710.3 → XP_006505773.1  zinc finger protein 638 isoform X10

      UniProtKB/Swiss-Prot
      Q61464, Q6DFV9, Q8C941
      Conserved Domains (6) summary
      smart00451
      Location:1858 → 1890
      ZnF_U1; U1-like zinc finger
      COG5180
      Location:1043 → 1386
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd12436
      Location:955 → 1028
      RRM1_2_MATR3_like; RNA recognition motif 1 and 2 in the matrin 3 family of nuclear proteins
      cd12716
      Location:851 → 925
      RRM1_2_NP220; RNA recognition motif 1 and 2 in vertebrate nuclear protein 220 (NP220)
      TIGR01649
      Location:852 → 1152
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cl17169
      Location:676 → 751
      RRM_SF; RNA recognition motif (RRM) superfamily

    RNA

    1. XR_004942919.1 RNA Sequence

    2. XR_001785106.3 RNA Sequence

    3. XR_004942920.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q61464.2 GenPept UniProtKB/Swiss-Prot:Q61464

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