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    Tmem218 transmembrane protein 218 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300516, updated on 27-Nov-2024

    Summary

    Official Symbol
    Tmem218provided by RGD
    Official Full Name
    transmembrane protein 218provided by RGD
    Primary source
    RGD:1311364
    See related
    AllianceGenome:RGD:1311364
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311364
    Summary
    Predicted to be located in cilium and membrane. Human ortholog(s) of this gene implicated in Joubert syndrome. Orthologous to human TMEM218 (transmembrane protein 218). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 51.1), Heart (RPKM 47.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem218 in Genome Data Viewer
    Location:
    8q22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (45113368..45128739)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (36924553..36940564)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (39687280..39702722)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene PBX/knotted 1 homeobox 2 Neighboring gene uncharacterized LOC120094114 Neighboring gene uncharacterized LOC108351675 Neighboring gene solute carrier family 37 member 2 Neighboring gene coiled-coil domain containing 15 Neighboring gene transfer RNA proline (anticodon AGG) 64

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008325.1NP_001008326.1  transmembrane protein 218

      See identical proteins and their annotated locations for NP_001008326.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085342
      UniProtKB/Swiss-Prot
      Q5U3Y9
      UniProtKB/TrEMBL
      A6KRM2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      45113368..45128739
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008766050.4XP_008764272.1  transmembrane protein 218 isoform X1

      See identical proteins and their annotated locations for XP_008764272.1

      UniProtKB/Swiss-Prot
      Q5U3Y9
      UniProtKB/TrEMBL
      A6KRM2