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    Ciart circadian associated repressor of transcription [ Mus musculus (house mouse) ]

    Gene ID: 229599, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ciartprovided by MGI
    Official Full Name
    circadian associated repressor of transcriptionprovided by MGI
    Primary source
    MGI:MGI:2684975
    See related
    Ensembl:ENSMUSG00000038550 AllianceGenome:MGI:2684975
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm129; Chrono
    Summary
    Enables E-box binding activity. Involved in circadian regulation of gene expression; locomotor rhythm; and negative regulation of DNA-templated transcription. Located in nucleus. Orthologous to human CIART (circadian associated repressor of transcription). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in bladder adult (RPKM 9.0), cortex adult (RPKM 8.4) and 20 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ciart in Genome Data Viewer
    Location:
    3 F2.1; 3 41.42 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (95785812..95790012, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (95878500..95882257, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene pre-mRNA processing factor 3 Neighboring gene STARR-positive B cell enhancer ABC_E10199 Neighboring gene RIKEN cDNA C920021L13 gene Neighboring gene mitochondrial ribosomal protein S21 Neighboring gene STARR-positive B cell enhancer ABC_E9562 Neighboring gene cDNA sequence BC028528 Neighboring gene STARR-positive B cell enhancer ABC_E2673 Neighboring gene aph1 homolog A, gamma secretase subunit Neighboring gene carbonic anhydrase 14 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:95732686-95732932 Neighboring gene predicted gene, 46815

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (5) 
    • Gene trapped (1) 
    • Targeted (2) 

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in PML body  
    is_active_in nucleus  
    located_in nucleus PubMed 

    General protein information

    Preferred Names
    circadian-associated transcriptional repressor
    Names
    chIP-derived repressor of network oscillator
    computationally highlighted repressor of the network oscillator

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033302.3NP_001028474.1  circadian-associated transcriptional repressor isoform 1

      See identical proteins and their annotated locations for NP_001028474.1

      Status: VALIDATED

      Source sequence(s)
      AC092855
      Consensus CDS
      CCDS50997.1
      UniProtKB/Swiss-Prot
      Q3TQ03, Q3U1B8
      UniProtKB/TrEMBL
      A2RTE4
      Related
      ENSMUSP00000049308.4, ENSMUST00000036418.10
      Conserved Domains (1) summary
      pfam15673
      Location:85360
      Ciart; Circadian-associated transcriptional repressor
    2. NM_001411319.1NP_001398248.1  circadian-associated transcriptional repressor isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC092855
      UniProtKB/Swiss-Prot
      Q3TQ03, Q3U1B8
      UniProtKB/TrEMBL
      A2RTE4
    3. NM_001411320.1NP_001398249.1  circadian-associated transcriptional repressor isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC092855
      UniProtKB/Swiss-Prot
      Q3TQ03, Q3U1B8
      UniProtKB/TrEMBL
      A2RTE4
    4. NM_001411321.1NP_001398250.1  circadian-associated transcriptional repressor isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC092855
      UniProtKB/Swiss-Prot
      Q3TQ03, Q3U1B8
      UniProtKB/TrEMBL
      A2RTE4
    5. NM_001411322.1NP_001398251.1  circadian-associated transcriptional repressor isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC092855
      UniProtKB/Swiss-Prot
      Q3TQ03, Q3U1B8
      UniProtKB/TrEMBL
      A2RTE4
    6. NM_001411323.1NP_001398252.1  circadian-associated transcriptional repressor isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC092855
      UniProtKB/Swiss-Prot
      Q3TQ03, Q3U1B8
      UniProtKB/TrEMBL
      A2RTE4
      Related
      ENSMUSP00000124943.2, ENSMUST00000159739.8
    7. NM_001411324.1NP_001398253.1  circadian-associated transcriptional repressor isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC092855
    8. NM_001411325.1NP_001398254.1  circadian-associated transcriptional repressor isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC092855
    9. NM_001411326.1NP_001398255.1  circadian-associated transcriptional repressor isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC092855
    10. NM_001411327.1NP_001398256.1  circadian-associated transcriptional repressor isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC092855
    11. NM_001411328.1NP_001398257.1  circadian-associated transcriptional repressor isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC092855
    12. NM_001411329.1NP_001398258.1  circadian-associated transcriptional repressor isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC092855
    13. NM_001411330.1NP_001398259.1  circadian-associated transcriptional repressor isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC092855

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      95785812..95790012 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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