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    Mageh1 MAGE family member H1 [ Mus musculus (house mouse) ]

    Gene ID: 75625, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Mageh1provided by MGI
    Official Full Name
    MAGE family member H1provided by MGI
    Primary source
    MGI:MGI:1922875
    See related
    Ensembl:ENSMUSG00000047238 AllianceGenome:MGI:1922875
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    APR1; APR-1; 2010107K23Rik
    Summary
    Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; egg cylinder; genitourinary system; nervous system; and sensory organ. Orthologous to human MAGEH1 (MAGE family member H1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human all
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    Genomic context

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    See Mageh1 in Genome Data Viewer
    Location:
    X F3; X 68.46 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (151819162..151820559, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (153036166..153037563, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene ribosomal protein L7A, pseudogene 12 Neighboring gene ribosomal protein S7, pseudogene 3 Neighboring gene STARR-seq mESC enhancer starr_48108 Neighboring gene ubiquitin specific protease 51 Neighboring gene RIKEN cDNA 9530051G07 gene Neighboring gene predicted pseudogene 5396

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression dynamics of Mage family genes during self-renewal and differentiation of mouse pluripotent stem and teratocarcinoma cells. Gordeeva O, et al. Oncotarget, 2019 May 14. PMID 31143371, Free PMC Article
    2. A genomic atlas of mouse hypothalamic development. Shimogori T, et al. Nat Neurosci, 2010 Jun. PMID 20436479, Free PMC Article
    3. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
    4. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    5. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    melanoma-associated antigen H1
    Names
    MAGE-H1 antigen
    melanoma antigen, family H, 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023788.3 → NP_076277.1  melanoma-associated antigen H1

      Status: VALIDATED

      Source sequence(s)
      BC051935, CD363769
      Consensus CDS
      CCDS30478.1
      UniProtKB/Swiss-Prot
      Q99PB0, Q9NWG9
      UniProtKB/TrEMBL
      Q3UKU3
      Related
      ENSMUSP00000057157.4, ENSMUST00000051484.5
      Conserved Domains (1) summary
      pfam01454
      Location:55 → 169
      MAGE; MAGE family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      151819162..151820559 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9NWG9.1 GenPept UniProtKB/Swiss-Prot:Q9NWG9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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