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    Tmem42 transmembrane protein 42 [ Mus musculus (house mouse) ]

    Gene ID: 66079, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tmem42provided by MGI
    Official Full Name
    transmembrane protein 42provided by MGI
    Primary source
    MGI:MGI:1277176
    See related
    Ensembl:ENSMUSG00000066233 AllianceGenome:MGI:1277176
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D9Ertd662e; 0610027O18Rik; 4933429E06Rik
    Summary
    Predicted to be located in membrane. Orthologous to human TMEM42 (transmembrane protein 42). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 30.6), lung adult (RPKM 16.5) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tmem42 in Genome Data Viewer
    Location:
    9 F4; 9 73.52 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (122850072..122852556)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (123021007..123023491)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1110059G10 gene Neighboring gene STARR-seq mESC enhancer starr_25555 Neighboring gene STARR-seq mESC enhancer starr_25556 Neighboring gene kinesin family member 15 Neighboring gene predicted gene, 35691 Neighboring gene predicted gene 9856 Neighboring gene transglutaminase 4 (prostate) Neighboring gene zinc finger, DHHC domain containing 3 Neighboring gene exosome component 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC29956

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 42

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164823.1 → NP_001158295.1  transmembrane protein 42 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to variant 1.
      Source sequence(s)
      AA939506, AC133650, AK012820, BX515032
      Consensus CDS
      CCDS90690.1
      UniProtKB/TrEMBL
      A0A1L1SRQ7
      Related
      ENSMUSP00000149571.2, ENSMUST00000213514.2

    2. NM_025339.4 → NP_079615.1  transmembrane protein 42 isoform 1

      See identical proteins and their annotated locations for NP_079615.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC133650, AK012820, BX515032
      Consensus CDS
      CCDS23652.1
      UniProtKB/Swiss-Prot
      Q9CR22
      Related
      ENSMUSP00000081784.6, ENSMUST00000084733.7

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      122850072..122852556
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512206.4 → XP_006512269.1  transmembrane protein 42 isoform X1

      See identical proteins and their annotated locations for XP_006512269.1

      UniProtKB/Swiss-Prot
      Q9CR22

    2. XM_006512205.3 → XP_006512268.1  transmembrane protein 42 isoform X1

      See identical proteins and their annotated locations for XP_006512268.1

      UniProtKB/Swiss-Prot
      Q9CR22
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CR22.1 GenPept UniProtKB/Swiss-Prot:Q9CR22

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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