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    Satl1 spermidine/spermine N1-acetyl transferase-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 302325, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Satl1provided by RGD
    Official Full Name
    spermidine/spermine N1-acetyl transferase-like 1provided by RGD
    Primary source
    RGD:1565932
    See related
    EnsemblRapid:ENSRNOG00000022476 AllianceGenome:RGD:1565932
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565932
    Summary
    Predicted to enable diamine N-acetyltransferase activity and spermidine binding activity. Predicted to be involved in spermidine acetylation. Orthologous to human SATL1 (spermidine/spermine N1-acetyl transferase like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 37.4), Muscle (RPKM 4.1) and 4 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Satl1 in Genome Data Viewer
    Location:
    Xq31
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (81645584..81661393, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (77453357..77469100, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (83772526..83788556, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene testis expressed gene 16 Neighboring gene ubiquitin-conjugating enzyme E2D 4 like 1 Neighboring gene apolipoprotein O-like Neighboring gene RIKEN cDNA 2010106E10 gene like Neighboring gene eukaryotic translation elongation factor 1 alpha 1, pseudogene 18

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables diamine N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables spermidine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in spermidine acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    spermidine/spermine N(1)-acetyltransferase-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163543.1 → NP_001157015.1  spermidine/spermine N(1)-acetyltransferase-like protein 1

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6IV98, D3ZA19
      Related
      ENSRNOP00000034830.4, ENSRNOT00000037149.7
      Conserved Domains (2) summary
      COG0456
      Location:594 → 731
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      pfam00583
      Location:657 → 731
      Acetyltransf_1; Acetyltransferase (GNAT) family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      81645584..81661393 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279890.1 → XP_063135960.1  spermidine/spermine N(1)-acetyltransferase-like protein 1 isoform X3

      UniProtKB/TrEMBL
      A6IV98

    2. XM_039099582.2 → XP_038955510.2  spermidine/spermine N(1)-acetyltransferase-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A6IV98
      Related
      ENSRNOP00000082605.2, ENSRNOT00000106441.2

    3. XM_063279889.1 → XP_063135959.1  spermidine/spermine N(1)-acetyltransferase-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZV75, A6IV98
      Related
      ENSRNOP00000100069.1, ENSRNOT00000144938.1
    Nucleotide Protein Strain
    Heading Accession and Version

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