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    Mansc1 MANSC domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690606, updated on 9-Dec-2024

    Summary

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    Symbol
    Mansc1provided by RGD
    Full Name
    MANSC domain containing 1provided by RGD
    Primary source
    RGD:1593458
    See related
    EnsemblRapid:ENSRNOG00000028526 AllianceGenome:RGD:1593458
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be active in Golgi apparatus. Orthologous to human MANSC1 (MANSC domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 15.9), Lung (RPKM 14.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mansc1 in Genome Data Viewer
    Location:
    4q43
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (169170164..169190379, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (167438817..167459047, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (168363192..168382605, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene LDL receptor related protein 6 Neighboring gene uncharacterized LOC102551409 Neighboring gene BLOC-1 related complex subunit 5 Neighboring gene dual specificity phosphatase 16 Neighboring gene cAMP responsive element binding protein-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    MANSC domain-containing protein 1
    NP_001103073.1
    XP_006237600.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109603.3 → NP_001103073.1  MANSC domain-containing protein 1 precursor

      See identical proteins and their annotated locations for NP_001103073.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A6IMD3, D4AE21
      Related
      ENSRNOP00000029997.2, ENSRNOT00000029510.6
      Conserved Domains (2) summary
      smart00765
      Location:23 → 116
      MANEC; The MANEC domain, formerly called MANSC
      cl07893
      Location:164 → 236
      AmyAc_family; Alpha amylase catalytic domain family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      169170164..169190379 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006237538.5 → XP_006237600.1  MANSC domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006237600.1

      UniProtKB/TrEMBL
      A6IMD3, D4AE21
      Conserved Domains (2) summary
      smart00765
      Location:23 → 116
      MANEC; The MANEC domain, formerly called MANSC
      cl07893
      Location:164 → 236
      AmyAc_family; Alpha amylase catalytic domain family
    Nucleotide Protein Strain
    Heading Accession and Version

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