4933405O20Rikl RIKEN cDNA 4933405O20 gene like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: 4933405O20Riklprovided by RGD
Official Full Name: RIKEN cDNA 4933405O20 gene likeprovided by RGD
Primary source: RGD:1642415
See related: AllianceGenome:RGD:1642415
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable magnesium ion binding activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to be active in mitochondrion. Orthologous to human IDH3G (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

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Location:: 1q22

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (109436262..109437732)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (100300241..100301711)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (105935449..105936919)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in isocitrate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in tricarboxylic acid cycle	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial

Names: NAD(+)-specific ICDH subunit gamma 2; isocitric dehydrogenase subunit gamma 2; probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial-like

NP_001096833.1

EC 1.1.1.41

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001103363.1 → NP_001096833.1 probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial

See identical proteins and their annotated locations for NP_001096833.1

Status: VALIDATED

Source sequence(s)

BC098006

UniProtKB/Swiss-Prot

Q4QQT5

UniProtKB/TrEMBL

Q3B8Q8

Conserved Domains (1) summary

cl00445
Location:49 → 380

Iso_dh; Isocitrate/isopropylmalate dehydrogenase