U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Xrra1 X-ray radiation resistance associated 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 365313, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    Xrra1provided by RGD
    Official Full Name
    X-ray radiation resistance associated 1provided by RGD
    Primary source
    RGD:1305502
    See related
    EnsemblRapid:ENSRNOG00000026503 AllianceGenome:RGD:1305502
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in response to X-ray. Predicted to be located in cytoplasm and nuclear body. Predicted to be active in nucleus. Orthologous to human XRRA1 (X-ray radiation resistance associated 1). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Testes (RPKM 62.8), Thymus (RPKM 42.2) and 9 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Xrra1 in Genome Data Viewer
    Location:
    1q32
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (163595403..163660003)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (154183330..154247883)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (164849833..164917570)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483763 Neighboring gene signal peptidase complex subunit 2 Neighboring gene uncharacterized LOC102547456 Neighboring gene ring finger protein 169 Neighboring gene small nucleolar RNA SNORA20 Neighboring gene Set nuclear proto-oncogene, pseudogene 4

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis. Mesak FM, et al. BMC Genomics, 2003 Aug 9. PMID 12908878, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in response to X-ray ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    X-ray radiation resistance-associated protein 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432344.1 → NP_001419273.1  X-ray radiation resistance-associated protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A0G2K0N1

    2. NM_001432345.1 → NP_001419274.1  X-ray radiation resistance-associated protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001

    3. NM_001432346.1 → NP_001419275.1  X-ray radiation resistance-associated protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      163595403..163660003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003748930.6 → XP_003748978.1  X-ray radiation resistance-associated protein 1 isoform X1

      Related
      ENSRNOP00000071512.2, ENSRNOT00000087818.3
      Conserved Domains (3) summary
      cd00116
      Location:139 → 270
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:147 → 169
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:192 → 270
      LRR_8; Leucine rich repeat

    2. XM_006229821.5 → XP_006229883.1  X-ray radiation resistance-associated protein 1 isoform X2

      Conserved Domains (3) summary
      cd00116
      Location:96 → 227
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:104 → 126
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:149 → 227
      LRR_8; Leucine rich repeat

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001113753.1: Suppressed sequence

      Description
      NM_001113753.1: This RefSeq was temporarily suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools