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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_009892.1 RefSeqGene
- Range
-
5001..35600
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_75
mRNA and Protein(s)
-
NM_001114182.3 → NP_001107654.1 interleukin-1 receptor-associated kinase 4 isoform a
See identical proteins and their annotated locations for NP_001107654.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1, 2, and 13 all encode the same isoform (a).
- Source sequence(s)
-
AC093012, AI126481, AK304583, AY340963
- Consensus CDS
-
CCDS8744.1
- UniProtKB/Swiss-Prot
- Q69FE1, Q8TDF7, Q9NWZ3, Q9Y589
- UniProtKB/TrEMBL
- B2RAP9, Q69FE3
- Related
- ENSP00000446490.1, ENST00000551736.5
- Conserved Domains (2) summary
-
- cd08793
Location:9 → 106
- Death_IRAK4; Death domain of Interleukin-1 Receptor-Associated Kinase 4
- cd14158
Location:170 → 457
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
NM_001145256.2 → NP_001138728.1 interleukin-1 receptor-associated kinase 4 isoform b
See identical proteins and their annotated locations for NP_001138728.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an alternate exon and uses a downstream start codon, compared to variant 1. The resulting isoform (b), also known as the short form, has a shorter N-terminus, compared to isoform a. Variants 3-10 all encode the same isoform (b).
- Source sequence(s)
-
AC093012, AI126481, AK304583, AY340965
- Consensus CDS
-
CCDS44862.1
- UniProtKB/TrEMBL
-
B4E359
- Conserved Domains (1) summary
-
- cd14158
Location:46 → 333
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
NM_001145257.2 → NP_001138729.1 interleukin-1 receptor-associated kinase 4 isoform b
See identical proteins and their annotated locations for NP_001138729.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks two alternate exons and uses a downstream start codon, compared to variant 1. The resulting isoform (b), also known as the short form, has a shorter N-terminus, compared to isoform a. Variants 3-10 all encode the same isoform (b).
- Source sequence(s)
-
AC093012, AI126481, AK299944
- Consensus CDS
-
CCDS44862.1
- UniProtKB/TrEMBL
-
B4E359
- Conserved Domains (1) summary
-
- cd14158
Location:46 → 333
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
NM_001145258.2 → NP_001138730.1 interleukin-1 receptor-associated kinase 4 isoform b
See identical proteins and their annotated locations for NP_001138730.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks three alternate exons and uses a downstream start codon, compared to variant 1. The resulting isoform (b), also known as the short form, has a shorter N-terminus, compared to isoform a. Variants 3-10 all encode the same isoform (b).
- Source sequence(s)
-
AC093012, AI126481, AK304583
- Consensus CDS
-
CCDS44862.1
- UniProtKB/TrEMBL
-
B4E359
- Related
- ENSP00000408734.2, ENST00000440781.6
- Conserved Domains (1) summary
-
- cd14158
Location:46 → 333
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
NM_001351338.2 → NP_001338267.1 interleukin-1 receptor-associated kinase 4 isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (6), as well as variants 3-5 and 7-10, encodes isoform b.
- Source sequence(s)
-
AC093012, AK027301
- Consensus CDS
-
CCDS44862.1
- UniProtKB/TrEMBL
-
B4E359
- Conserved Domains (1) summary
-
- cd14158
Location:46 → 333
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
NM_001351339.2 → NP_001338268.1 interleukin-1 receptor-associated kinase 4 isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (7), as well as variants 3-6 and 8-10, encodes isoform b.
- Source sequence(s)
-
AC093012, AY340967
- Consensus CDS
-
CCDS44862.1
- UniProtKB/TrEMBL
-
B4E359
- Conserved Domains (1) summary
-
- cd14158
Location:46 → 333
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
NM_001351340.2 → NP_001338269.1 interleukin-1 receptor-associated kinase 4 isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (8), as well as variants 3-7, 9, and 10, encodes isoform b.
- Source sequence(s)
-
AC093012
- Consensus CDS
-
CCDS44862.1
- UniProtKB/TrEMBL
-
B4E359
- Conserved Domains (1) summary
-
- cd14158
Location:46 → 333
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
NM_001351341.2 → NP_001338270.1 interleukin-1 receptor-associated kinase 4 isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (9), as well as variants 3-8 and 10, encodes isoform b.
- Source sequence(s)
-
AC093012
- Consensus CDS
-
CCDS44862.1
- UniProtKB/TrEMBL
-
B4E359
- Conserved Domains (1) summary
-
- cd14158
Location:46 → 333
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
NM_001351342.2 → NP_001338271.1 interleukin-1 receptor-associated kinase 4 isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (10), as well as variants 3-9, encodes isoform b.
- Source sequence(s)
-
AC093012
- Consensus CDS
-
CCDS44862.1
- UniProtKB/TrEMBL
-
B4E359
- Conserved Domains (1) summary
-
- cd14158
Location:46 → 333
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
NM_001351343.2 → NP_001338272.1 interleukin-1 receptor-associated kinase 4 isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (11), as well as variant 12, encodes isoform c.
- Source sequence(s)
-
AC093012
- Conserved Domains (1) summary
-
- cl21453
Location:12 → 254
- PKc_like; Protein Kinases, catalytic domain
-
NM_001351344.2 → NP_001338273.1 interleukin-1 receptor-associated kinase 4 isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (12), as well as variant 11, encodes isoform c.
- Source sequence(s)
-
AC093012
- Conserved Domains (1) summary
-
- cl21453
Location:12 → 254
- PKc_like; Protein Kinases, catalytic domain
-
NM_001351345.2 → NP_001338274.1 interleukin-1 receptor-associated kinase 4 isoform a
Status: REVIEWED
- Description
- Transcript Variant: This variant (13), as well as variants 1 and 2, encodes isoform a.
- Source sequence(s)
-
AC093012
- Consensus CDS
-
CCDS8744.1
- UniProtKB/Swiss-Prot
- Q69FE1, Q8TDF7, Q9NWZ3, Q9Y589
- UniProtKB/TrEMBL
- B2RAP9, Q69FE3
- Conserved Domains (2) summary
-
- cd08793
Location:9 → 106
- Death_IRAK4; Death domain of Interleukin-1 Receptor-Associated Kinase 4
- cd14158
Location:170 → 457
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
NM_016123.4 → NP_057207.2 interleukin-1 receptor-associated kinase 4 isoform a
See identical proteins and their annotated locations for NP_057207.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 13 all encode the same isoform (a).
- Source sequence(s)
-
AC093012, AI126481, AK304583, AK314288, BC013316
- Consensus CDS
-
CCDS8744.1
- UniProtKB/Swiss-Prot
- Q69FE1, Q8TDF7, Q9NWZ3, Q9Y589
- UniProtKB/TrEMBL
- B2RAP9, Q69FE3
- Related
- ENSP00000479889.3, ENST00000613694.5
- Conserved Domains (2) summary
-
- cd08793
Location:9 → 106
- Death_IRAK4; Death domain of Interleukin-1 Receptor-Associated Kinase 4
- cd14158
Location:170 → 457
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000012.12 Reference GRCh38.p14 Primary Assembly
- Range
-
43758951..43789541
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011538431.3 → XP_011536733.1 interleukin-1 receptor-associated kinase 4 isoform X1
See identical proteins and their annotated locations for XP_011536733.1
- UniProtKB/Swiss-Prot
- Q69FE1, Q8TDF7, Q9NWZ3, Q9Y589
- UniProtKB/TrEMBL
- B2RAP9, Q69FE3
- Conserved Domains (2) summary
-
- cd08793
Location:9 → 106
- Death_IRAK4; Death domain of Interleukin-1 Receptor-Associated Kinase 4
- cd14158
Location:170 → 457
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
XM_006719438.4 → XP_006719501.1 interleukin-1 receptor-associated kinase 4 isoform X1
See identical proteins and their annotated locations for XP_006719501.1
- UniProtKB/Swiss-Prot
- Q69FE1, Q8TDF7, Q9NWZ3, Q9Y589
- UniProtKB/TrEMBL
- B2RAP9, Q69FE3
- Conserved Domains (2) summary
-
- cd08793
Location:9 → 106
- Death_IRAK4; Death domain of Interleukin-1 Receptor-Associated Kinase 4
- cd14158
Location:170 → 457
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
XM_005268945.5 → XP_005269002.1 interleukin-1 receptor-associated kinase 4 isoform X1
See identical proteins and their annotated locations for XP_005269002.1
- UniProtKB/Swiss-Prot
- Q69FE1, Q8TDF7, Q9NWZ3, Q9Y589
- UniProtKB/TrEMBL
- B2RAP9, Q69FE3
- Conserved Domains (2) summary
-
- cd08793
Location:9 → 106
- Death_IRAK4; Death domain of Interleukin-1 Receptor-Associated Kinase 4
- cd14158
Location:170 → 457
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
XM_005268943.4 → XP_005269000.1 interleukin-1 receptor-associated kinase 4 isoform X1
See identical proteins and their annotated locations for XP_005269000.1
- UniProtKB/Swiss-Prot
- Q69FE1, Q8TDF7, Q9NWZ3, Q9Y589
- UniProtKB/TrEMBL
- B2RAP9, Q69FE3
- Conserved Domains (2) summary
-
- cd08793
Location:9 → 106
- Death_IRAK4; Death domain of Interleukin-1 Receptor-Associated Kinase 4
- cd14158
Location:170 → 457
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
XM_017019390.3 → XP_016874879.1 interleukin-1 receptor-associated kinase 4 isoform X1
- UniProtKB/Swiss-Prot
- Q69FE1, Q8TDF7, Q9NWZ3, Q9Y589
- UniProtKB/TrEMBL
- B2RAP9, Q69FE3
- Conserved Domains (2) summary
-
- cd08793
Location:9 → 106
- Death_IRAK4; Death domain of Interleukin-1 Receptor-Associated Kinase 4
- cd14158
Location:170 → 457
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
-
XM_005268944.5 → XP_005269001.1 interleukin-1 receptor-associated kinase 4 isoform X1
See identical proteins and their annotated locations for XP_005269001.1
- UniProtKB/Swiss-Prot
- Q69FE1, Q8TDF7, Q9NWZ3, Q9Y589
- UniProtKB/TrEMBL
- B2RAP9, Q69FE3
- Conserved Domains (2) summary
-
- cd08793
Location:9 → 106
- Death_IRAK4; Death domain of Interleukin-1 Receptor-Associated Kinase 4
- cd14158
Location:170 → 457
- STKc_IRAK4; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 4
Alternate T2T-CHM13v2.0
Genomic
-
NC_060936.1 Alternate T2T-CHM13v2.0
- Range
-
43717649..43748266
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054372174.1 → XP_054228149.1 interleukin-1 receptor-associated kinase 4 isoform X1
- UniProtKB/TrEMBL
-
B2RAP9
-
XM_054372177.1 → XP_054228152.1 interleukin-1 receptor-associated kinase 4 isoform X1
- UniProtKB/TrEMBL
-
B2RAP9
-
XM_054372176.1 → XP_054228151.1 interleukin-1 receptor-associated kinase 4 isoform X1
- UniProtKB/TrEMBL
-
B2RAP9
-
XM_054372178.1 → XP_054228153.1 interleukin-1 receptor-associated kinase 4 isoform X1
- UniProtKB/TrEMBL
-
B2RAP9
-
XM_054372175.1 → XP_054228150.1 interleukin-1 receptor-associated kinase 4 isoform X1
- UniProtKB/TrEMBL
-
B2RAP9
-
XM_054372179.1 → XP_054228154.1 interleukin-1 receptor-associated kinase 4 isoform X1
- UniProtKB/TrEMBL
-
B2RAP9