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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001042417.2 → NP_001035882.1 RUN and FYVE domain-containing protein 2 isoform b
See identical proteins and their annotated locations for NP_001035882.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) uses an alternate first exon, lacks an alternate in-frame exon, and contains an alternate last exon in place of the last several exons compared to variant 1. The resulting isoform (b) has shorter and distinct N- and C-termini and lacks an alternate internal segment compared to isoform a.
- Source sequence(s)
-
BC041092, BM150360
- Consensus CDS
-
CCDS44414.1
- UniProtKB/TrEMBL
-
Q5GIA6
- Related
- ENSP00000382151.2, ENST00000399200.7
- Conserved Domains (2) summary
-
- COG1196
Location:176 → 380
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cl02689
Location:45 → 132
- RUN; RUN domain
-
NM_001278225.2 → NP_001265154.1 RUN and FYVE domain-containing protein 2 isoform c
See identical proteins and their annotated locations for NP_001265154.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) uses an alternate first exon, lacks an alternate in-frame exon, and contains an alternate last exon in place of the last several exons compared to variant 1. The resulting isoform (c) has shorter and distinct N- and C-termini and lacks an alternate internal segment compared to isoform a.
- Source sequence(s)
-
AK294211, BC041092
- Consensus CDS
-
CCDS60544.1
- UniProtKB/TrEMBL
-
Q5GIA6
- Related
- ENSP00000404986.2, ENST00000454950.6
- Conserved Domains (2) summary
-
- COG1196
Location:172 → 356
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- pfam02759
Location:1 → 108
- RUN; RUN domain
-
NM_001330103.2 → NP_001317032.1 RUN and FYVE domain-containing protein 2 isoform d
Status: VALIDATED
- Description
- Transcript Variant: This variant (6) uses an alternate 5'-terminal exon, resulting in a different 5' UTR and use of an alternate start codon compared to variant 1. It encodes isoform d, which has a distinct N-terminus and is shorter than isoform d.
- Source sequence(s)
-
AC016395, AF411980, AL136233, AY528716, BM998747
- Consensus CDS
-
CCDS81470.1
- UniProtKB/Swiss-Prot
- B3KXB2, B4DFR0, Q5TC48, Q8IW33, Q8WXA3, Q96P51, Q9P1Z1
- UniProtKB/TrEMBL
-
H0YD93
- Related
- ENSP00000473462.1, ENST00000602465.6
- Conserved Domains (3) summary
-
- COG1196
Location:230 → 536
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd15759
Location:534 → 604
- FYVE_RUFY2; FYVE domain found in RUN and FYVE domain-containing protein 2 (RUFY2) and similar proteins
- pfam02759
Location:45 → 166
- RUN; RUN domain
-
NM_017987.5 → NP_060457.4 RUN and FYVE domain-containing protein 2 isoform a
See identical proteins and their annotated locations for NP_060457.4
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
- Source sequence(s)
-
AC016395, AK127019, AL136233, BG681628, BQ006812
- Consensus CDS
-
CCDS41534.1
- UniProtKB/TrEMBL
-
H0YD93
- Related
- ENSP00000373420.2, ENST00000388768.6
- Conserved Domains (3) summary
-
- COG1196
Location:245 → 571
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd15759
Location:569 → 639
- FYVE_RUFY2; FYVE domain found in RUN and FYVE domain-containing protein 2 (RUFY2) and similar proteins
- pfam02759
Location:80 → 201
- RUN; RUN domain
RNA
-
NR_103475.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) differs in the 5' and 3' ends compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AB040970, AC016395, AK127019, AL136233
- Related
-
ENST00000466493.5
-
NR_103476.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) differs in the 5' and 3' ends compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC016395, AF461266, BM150360, DA858392
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000010.11 Reference GRCh38.p14 Primary Assembly
- Range
-
68341112..68407277 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047425448.1 → XP_047281404.1 RUN and FYVE domain-containing protein 2 isoform X9
- UniProtKB/TrEMBL
-
H0YD93
-
XM_005269957.6 → XP_005270014.1 RUN and FYVE domain-containing protein 2 isoform X5
See identical proteins and their annotated locations for XP_005270014.1
- UniProtKB/TrEMBL
-
H0YD93
- Conserved Domains (3) summary
-
- COG1196
Location:196 → 502
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd15759
Location:500 → 570
- FYVE_RUFY2; FYVE domain found in RUN and FYVE domain-containing protein 2 (RUFY2) and similar proteins
- cl02689
Location:45 → 132
- RUN; RUN domain
-
XM_047425446.1 → XP_047281402.1 RUN and FYVE domain-containing protein 2 isoform X7
- UniProtKB/TrEMBL
-
H0YD93
-
XM_047425445.1 → XP_047281401.1 RUN and FYVE domain-containing protein 2 isoform X6
- UniProtKB/TrEMBL
-
H0YD93
-
XM_005269953.5 → XP_005270010.1 RUN and FYVE domain-containing protein 2 isoform X1
See identical proteins and their annotated locations for XP_005270010.1
- UniProtKB/TrEMBL
-
H0YD93
- Conserved Domains (3) summary
-
- COG1196
Location:231 → 537
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd15759
Location:535 → 605
- FYVE_RUFY2; FYVE domain found in RUN and FYVE domain-containing protein 2 (RUFY2) and similar proteins
- cl02689
Location:80 → 167
- RUN; RUN domain
-
XM_005269956.5 → XP_005270013.1 RUN and FYVE domain-containing protein 2 isoform X4
- UniProtKB/TrEMBL
-
H0YD93
- Conserved Domains (6) summary
-
- cd15759
Location:513 → 583
- FYVE_RUFY2; FYVE domain found in RUN and FYVE domain-containing protein 2 (RUFY2) and similar proteins
- pfam02759
Location:80 → 203
- RUN; RUN domain
- pfam06156
Location:258 → 335
- DUF972; Protein of unknown function (DUF972)
- pfam09728
Location:233 → 514
- Taxilin; Myosin-like coiled-coil protein
- pfam16505
Location:329 → 408
- Emaravirus_P4; P4 movement protein of Emaravirus, and the 30K superfamily
- cl19219
Location:355 → 484
- DUF342; Protein of unknown function (DUF342)
-
XM_047425444.1 → XP_047281400.1 RUN and FYVE domain-containing protein 2 isoform X2
- UniProtKB/Swiss-Prot
- B3KXB2, B4DFR0, Q5TC48, Q8IW33, Q8WXA3, Q96P51, Q9P1Z1
- UniProtKB/TrEMBL
-
H0YD93
-
XM_047425447.1 → XP_047281403.1 RUN and FYVE domain-containing protein 2 isoform X8
- UniProtKB/TrEMBL
-
H0YD93
-
XM_011539942.3 → XP_011538244.1 RUN and FYVE domain-containing protein 2 isoform X2
See identical proteins and their annotated locations for XP_011538244.1
- UniProtKB/Swiss-Prot
- B3KXB2, B4DFR0, Q5TC48, Q8IW33, Q8WXA3, Q96P51, Q9P1Z1
- UniProtKB/TrEMBL
-
H0YD93
- Conserved Domains (3) summary
-
- COG1196
Location:230 → 536
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd15759
Location:534 → 604
- FYVE_RUFY2; FYVE domain found in RUN and FYVE domain-containing protein 2 (RUFY2) and similar proteins
- pfam02759
Location:45 → 166
- RUN; RUN domain
-
XM_005269955.5 → XP_005270012.1 RUN and FYVE domain-containing protein 2 isoform X3
See identical proteins and their annotated locations for XP_005270012.1
- UniProtKB/TrEMBL
-
H0YD93
- Conserved Domains (3) summary
-
- COG1196
Location:214 → 520
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd15759
Location:518 → 588
- FYVE_RUFY2; FYVE domain found in RUN and FYVE domain-containing protein 2 (RUFY2) and similar proteins
- pfam02759
Location:29 → 150
- RUN; RUN domain
-
XM_047425456.1 → XP_047281412.1 RUN and FYVE domain-containing protein 2 isoform X17
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_047425455.1 → XP_047281411.1 RUN and FYVE domain-containing protein 2 isoform X16
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_047425450.1 → XP_047281406.1 RUN and FYVE domain-containing protein 2 isoform X11
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_047425457.1 → XP_047281413.1 RUN and FYVE domain-containing protein 2 isoform X18
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_047425452.1 → XP_047281408.1 RUN and FYVE domain-containing protein 2 isoform X13
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_047425451.1 → XP_047281407.1 RUN and FYVE domain-containing protein 2 isoform X12
-
XM_047425454.1 → XP_047281410.1 RUN and FYVE domain-containing protein 2 isoform X15
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_047425449.1 → XP_047281405.1 RUN and FYVE domain-containing protein 2 isoform X10
-
XM_047425453.1 → XP_047281409.1 RUN and FYVE domain-containing protein 2 isoform X14
- UniProtKB/TrEMBL
-
Q5GIA6
Alternate T2T-CHM13v2.0
Genomic
-
NC_060934.1 Alternate T2T-CHM13v2.0
- Range
-
69210323..69276503 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054366258.1 → XP_054222233.1 RUN and FYVE domain-containing protein 2 isoform X9
- UniProtKB/TrEMBL
-
H0YD93
-
XM_054366254.1 → XP_054222229.1 RUN and FYVE domain-containing protein 2 isoform X5
- UniProtKB/TrEMBL
-
H0YD93
-
XM_054366256.1 → XP_054222231.1 RUN and FYVE domain-containing protein 2 isoform X7
- UniProtKB/TrEMBL
-
H0YD93
-
XM_054366255.1 → XP_054222230.1 RUN and FYVE domain-containing protein 2 isoform X6
- UniProtKB/TrEMBL
-
H0YD93
-
XM_054366250.1 → XP_054222225.1 RUN and FYVE domain-containing protein 2 isoform X1
- UniProtKB/TrEMBL
-
H0YD93
-
XM_054366253.1 → XP_054222228.1 RUN and FYVE domain-containing protein 2 isoform X4
- UniProtKB/TrEMBL
-
H0YD93
-
XM_054366251.1 → XP_054222226.1 RUN and FYVE domain-containing protein 2 isoform X2
- UniProtKB/Swiss-Prot
- B3KXB2, B4DFR0, Q5TC48, Q8IW33, Q8WXA3, Q96P51, Q9P1Z1
- UniProtKB/TrEMBL
-
H0YD93
-
XM_054366257.1 → XP_054222232.1 RUN and FYVE domain-containing protein 2 isoform X8
- UniProtKB/TrEMBL
-
H0YD93
-
XM_054366252.1 → XP_054222227.1 RUN and FYVE domain-containing protein 2 isoform X3
- UniProtKB/TrEMBL
-
H0YD93
-
XM_054366266.1 → XP_054222241.1 RUN and FYVE domain-containing protein 2 isoform X17
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_054366265.1 → XP_054222240.1 RUN and FYVE domain-containing protein 2 isoform X16
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_054366260.1 → XP_054222235.1 RUN and FYVE domain-containing protein 2 isoform X11
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_054366267.1 → XP_054222242.1 RUN and FYVE domain-containing protein 2 isoform X18
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_054366262.1 → XP_054222237.1 RUN and FYVE domain-containing protein 2 isoform X13
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_054366261.1 → XP_054222236.1 RUN and FYVE domain-containing protein 2 isoform X12
-
XM_054366264.1 → XP_054222239.1 RUN and FYVE domain-containing protein 2 isoform X15
- UniProtKB/TrEMBL
-
Q5GIA6
-
XM_054366259.1 → XP_054222234.1 RUN and FYVE domain-containing protein 2 isoform X10
-
XM_054366263.1 → XP_054222238.1 RUN and FYVE domain-containing protein 2 isoform X14
- UniProtKB/TrEMBL
-
Q5GIA6