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    Bnc2 basonuclin zinc finger protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298189, updated on 9-Dec-2024

    Summary

    Official Symbol
    Bnc2provided by RGD
    Official Full Name
    basonuclin zinc finger protein 2provided by RGD
    Primary source
    RGD:1310694
    See related
    EnsemblRapid:ENSRNOG00000006553 AllianceGenome:RGD:1310694
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable rDNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including endochondral bone growth; roof of mouth development; and tongue development. Predicted to be located in chromatin and nucleoplasm. Predicted to be active in nucleus. Orthologous to human BNC2 (basonuclin zinc finger protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Expression
    Biased expression in Kidney (RPKM 55.8), Uterus (RPKM 48.5) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Bnc2 in Genome Data Viewer
    Location:
    5q31
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (103724934..104061890, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (98679071..99016044, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (102407508..102807389, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC108350993 Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC103692399

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables rDNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within endochondral bone growth ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within mesenchyme development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    NOT acts_upstream_of_or_within regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within roof of mouth development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within tongue development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger protein basonuclin-2
    Names
    basonuclin 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106666.4NP_001100136.1  zinc finger protein basonuclin-2 isoform 1

      See identical proteins and their annotated locations for NP_001100136.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A8I5ZMQ2, A6J853, D3ZZ22
      Related
      ENSRNOP00000107024.1, ENSRNOT00000133529.1
      Conserved Domains (1) summary
      sd00017
      Location:10441065
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001415824.2NP_001402753.1  zinc finger protein basonuclin-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A8I5ZMQ2
      Related
      ENSRNOP00000112129.1, ENSRNOT00000132122.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      103724934..104061890 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)