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    Snurf SNRPN upstream open reading frame [ Rattus norvegicus (Norway rat) ]

    Gene ID: 113938, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Snurfprovided by RGD
    Official Full Name
    SNRPN upstream open reading frameprovided by RGD
    Primary source
    RGD:69269
    See related
    EnsemblRapid:ENSRNOG00000089795 AllianceGenome:RGD:69269
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable ATPase binding activity. Predicted to be located in nucleoplasm. Predicted to be active in nuclear speck. Orthologous to human SNURF (SNRPN upstream open reading frame). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 1941.8), Heart (RPKM 609.9) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Snurf in Genome Data Viewer
    Location:
    1q22
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (120316846..120339153, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (111101327..111123634, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (195074328..195096694, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, C/D box 64 Neighboring gene small nucleolar RNA, C/D box 107 Neighboring gene ras homolog family member G, pseudogene 3 Neighboring gene small nuclear ribonucleoprotein polypeptide N Neighboring gene uncharacterized LOC134483395 Neighboring gene COMM domain containing 9, pseudogene 1 Neighboring gene solute carrier family 25 member 19 like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Small nuclear RING finger protein stimulates the rat luteinizing hormone-beta promoter by interacting with Sp1 and steroidogenic factor-1 and protects from androgen suppression. Curtin D, et al. Mol Endocrinol, 2004 May. PMID 14988433
    2. An imprinted, mammalian bicistronic transcript encodes two independent proteins. Gray TA, et al. Proc Natl Acad Sci U S A, 1999 May 11. PMID 10318933, Free PMC Article
    3. Novel ATPase of SNF2-like protein family interacts with androgen receptor and modulates androgen-dependent transcription. Rouleau N, et al. Mol Biol Cell, 2002 Jun. PMID 12058073, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATPase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nuclear speck IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    SNRPN upstream reading frame protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001270712.1 → NP_001257641.1  SNRPN upstream reading frame protein

      See identical proteins and their annotated locations for NP_001257641.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein.
      Source sequence(s)
      BC098906, JAXUCZ010000001
      UniProtKB/Swiss-Prot
      Q9WU11
      Conserved Domains (1) summary
      pfam07192
      Location:4 → 68
      SNURF; SNURF/RPN4 protein

    2. NM_130738.2 → NP_570094.1  SNRPN upstream reading frame protein

      See identical proteins and their annotated locations for NP_570094.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants encode the same protein.
      Source sequence(s)
      BC081739, JAXUCZ010000001
      UniProtKB/Swiss-Prot
      Q9WU11
      Related
      ENSRNOP00000102778.1, ENSRNOT00000124842.1
      Conserved Domains (1) summary
      pfam07192
      Location:4 → 68
      SNURF; SNURF/RPN4 protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      120316846..120339153 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9WU11.1 GenPept UniProtKB/Swiss-Prot:Q9WU11

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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