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    Dip2c disco-interacting protein 2 homolog C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307067, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dip2cprovided by RGD
    Official Full Name
    disco-interacting protein 2 homolog Cprovided by RGD
    Primary source
    RGD:1560155
    See related
    EnsemblRapid:ENSRNOG00000015288 AllianceGenome:RGD:1560155
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560155
    Summary
    Orthologous to human DIP2C (disco interacting protein 2 homolog C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 320.5), Brain (RPKM 144.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Dip2c in Genome Data Viewer
    Location:
    17q12.1
    Exon count:
    42
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (65338711..65724111, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (60647346..61032467, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (63426688..63810183)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134482865 Neighboring gene zinc finger, MYND-type containing 11 Neighboring gene uncharacterized LOC108348621 Neighboring gene acireductone dioxygenase 1, pseudogene 1 Neighboring gene 60S ribosomal protein L22-like Neighboring gene La ribonucleoprotein 4B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. p38α MAPK proximity assay reveals a regulatory mechanism of alternative splicing in cardiomyocytes. Dumont AA, et al. Biochim Biophys Acta Mol Cell Res, 2019 Dec. PMID 31505169

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    disco-interacting protein 2 homolog C
    Names
    DIP2 disco-interacting protein 2 homolog C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107360.2 → NP_001100830.1  disco-interacting protein 2 homolog C isoform 1

      See identical proteins and their annotated locations for NP_001100830.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A8I6G2N3, A6KN16, D3ZZB0
      Related
      ENSRNOP00000106588.1, ENSRNOT00000173173.1
      Conserved Domains (5) summary
      cd05905
      Location:397 → 961
      Dip2; Disco-interacting protein 2 (Dip2)
      COG0318
      Location:373 → 964
      CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
      pfam00501
      Location:1032 → 1506
      AMP-binding; AMP-binding enzyme
      pfam06464
      Location:7 → 176
      DMAP_binding; DMAP1-binding Domain
      cl17068
      Location:1049 → 1601
      AFD_class_I; Adenylate forming domain, Class I superfamily

    2. NM_001415158.1 → NP_001402087.1  disco-interacting protein 2 homolog C isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A8I6G2N3
      Related
      ENSRNOP00000078375.2, ENSRNOT00000103716.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      65338711..65724111 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017600567.3 → XP_017456056.1  disco-interacting protein 2 homolog C isoform X5

      UniProtKB/TrEMBL
      A0A8I6G2N3

    2. XM_017600565.3 → XP_017456054.1  disco-interacting protein 2 homolog C isoform X2

      UniProtKB/TrEMBL
      A0A8I6G2N3

    3. XM_017600566.3 → XP_017456055.1  disco-interacting protein 2 homolog C isoform X3

      UniProtKB/TrEMBL
      A0A8I6G2N3
      Related
      ENSRNOP00000020634.7, ENSRNOT00000020634.8

    4. XM_039095749.2 → XP_038951677.1  disco-interacting protein 2 homolog C isoform X1

      UniProtKB/TrEMBL
      A0A8I6G2N3
      Conserved Domains (2) summary
      cd05905
      Location:1048 → 1622
      Dip2; Disco-interacting protein 2 (Dip2)
      pfam06464
      Location:8 → 174
      DMAP_binding; DMAP1-binding Domain

    5. XM_039095753.2 → XP_038951681.1  disco-interacting protein 2 homolog C isoform X7

      UniProtKB/TrEMBL
      A0A8I6G2N3
      Conserved Domains (1) summary
      cd05905
      Location:885 → 1459
      Dip2; Disco-interacting protein 2 (Dip2)

    6. XM_063276482.1 → XP_063132552.1  disco-interacting protein 2 homolog C isoform X7

      UniProtKB/TrEMBL
      A0A8I6G2N3

    7. XM_063276483.1 → XP_063132553.1  disco-interacting protein 2 homolog C isoform X7

      UniProtKB/TrEMBL
      A0A8I6G2N3

    8. XM_039095750.2 → XP_038951678.1  disco-interacting protein 2 homolog C isoform X4

      UniProtKB/TrEMBL
      A0A8I6G2N3
      Conserved Domains (2) summary
      cd05905
      Location:1033 → 1607
      Dip2; Disco-interacting protein 2 (Dip2)
      pfam06464
      Location:14 → 159
      DMAP_binding; DMAP1-binding Domain

    9. XM_039095751.2 → XP_038951679.1  disco-interacting protein 2 homolog C isoform X6

      UniProtKB/TrEMBL
      A0A8I6G2N3
      Conserved Domains (2) summary
      cd05905
      Location:977 → 1551
      Dip2; Disco-interacting protein 2 (Dip2)
      pfam06464
      Location:14 → 103
      DMAP_binding; DMAP1-binding Domain
    Nucleotide Protein Strain
    Heading Accession and Version

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