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    Ka11 type I keratin KA11 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 450226, updated on 9-Dec-2024

    Summary

    Symbol
    Ka11provided by RGD
    Full Name
    type I keratin KA11provided by RGD
    Primary source
    RGD:1359526
    See related
    EnsemblRapid:ENSRNOG00000071328 AllianceGenome:RGD:1359526
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Human ortholog(s) of this gene implicated in ectodermal dysplasia; focal nonepidermolytic palmoplantar keratoderma 1; and pachyonychia congenita. Orthologous to human KRT16 (keratin 16). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 6.4), Uterus (RPKM 5.4) and 5 other tissues See more
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    Genomic context

    See Ka11 in Genome Data Viewer
    Location:
    10q31
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (85661820..85667785, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (85161424..85164737, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (88141667..88144624, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene keratin 9 Neighboring gene keratin 14 Neighboring gene keratin 16 Neighboring gene keratin 17

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008750.1NP_001008750.1  type I keratin KA11

      See identical proteins and their annotated locations for NP_001008750.1

      Status: PROVISIONAL

      Source sequence(s)
      BK004048
      UniProtKB/TrEMBL
      A0A0G2JU48, F7EQ95, Q6IFV0
      Related
      ENSRNOP00000098609.2, ENSRNOT00000121066.2
      Conserved Domains (1) summary
      pfam00038
      Location:133441
      Filament; Intermediate filament protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      85661820..85667785 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063269573.1XP_063125643.1  type I keratin KA11 isoform X1